GPR146 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR107	GPR146	ENSP00000361483	ENSP00000380283	Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.669
GPR107	GPR153	ENSP00000361483	ENSP00000367125	Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).	Probable G-protein coupled receptor 153; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.448
GPR107	GPR162	ENSP00000361483	ENSP00000311528	Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).	Probable G-protein coupled receptor 162; Orphan receptor.	0.459
GPR107	GPR180	ENSP00000361483	ENSP00000366157	Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).	Integral membrane protein GPR180; G protein-coupled receptor 180.	0.599
GPR139	GPR146	ENSP00000458791	ENSP00000380283	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.542
GPR139	GPR148	ENSP00000458791	ENSP00000308908	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.	Probable G-protein coupled receptor 148; Orphan receptor.	0.505
GPR139	GPR153	ENSP00000458791	ENSP00000367125	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.	Probable G-protein coupled receptor 153; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.437
GPR139	GPR162	ENSP00000458791	ENSP00000311528	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.	Probable G-protein coupled receptor 162; Orphan receptor.	0.460
GPR142	GPR146	ENSP00000335158	ENSP00000380283	Probable G-protein coupled receptor 142; Orphan receptor.	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.455
GPR142	GPR148	ENSP00000335158	ENSP00000308908	Probable G-protein coupled receptor 142; Orphan receptor.	Probable G-protein coupled receptor 148; Orphan receptor.	0.453
GPR146	GPR107	ENSP00000380283	ENSP00000361483	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).	0.669
GPR146	GPR139	ENSP00000380283	ENSP00000458791	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.	0.542
GPR146	GPR142	ENSP00000380283	ENSP00000335158	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 142; Orphan receptor.	0.455
GPR146	GPR148	ENSP00000380283	ENSP00000308908	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 148; Orphan receptor.	0.464
GPR146	GPR153	ENSP00000380283	ENSP00000367125	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 153; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.435
GPR146	GPR162	ENSP00000380283	ENSP00000311528	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Probable G-protein coupled receptor 162; Orphan receptor.	0.518
GPR146	GPR180	ENSP00000380283	ENSP00000366157	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Integral membrane protein GPR180; G protein-coupled receptor 180.	0.450
GPR146	HTR5A	ENSP00000380283	ENSP00000287907	Probable G-protein coupled receptor 146; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	5-hydroxytryptamine receptor 5A; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins; Belongs to the G-protein coupled receptor 1 family.	0.461
GPR148	GPR139	ENSP00000308908	ENSP00000458791	Probable G-protein coupled receptor 148; Orphan receptor.	Probable G-protein coupled receptor 139; Orphan receptor. Seems to act through a G(q/11)-mediated pathway.	0.505
GPR148	GPR142	ENSP00000308908	ENSP00000335158	Probable G-protein coupled receptor 148; Orphan receptor.	Probable G-protein coupled receptor 142; Orphan receptor.	0.453