node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMPH | ARL16 | ENSP00000348602 | ENSP00000380635 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.629 |
ARL10 | ARL13A | ENSP00000308496 | ENSP00000398637 | ADP-ribosylation factor-like protein 10; ADP ribosylation factor like GTPase 10; Belongs to the small GTPase superfamily. Arf family. | ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A. | 0.548 |
ARL10 | ARL16 | ENSP00000308496 | ENSP00000380635 | ADP-ribosylation factor-like protein 10; ADP ribosylation factor like GTPase 10; Belongs to the small GTPase superfamily. Arf family. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.659 |
ARL11 | ARL16 | ENSP00000282026 | ENSP00000380635 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor. Belongs to the small GTPase superfamily. Arf family. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.558 |
ARL13A | ARL10 | ENSP00000398637 | ENSP00000308496 | ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A. | ADP-ribosylation factor-like protein 10; ADP ribosylation factor like GTPase 10; Belongs to the small GTPase superfamily. Arf family. | 0.548 |
ARL13A | ARL16 | ENSP00000398637 | ENSP00000380635 | ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.684 |
ARL13A | PDE6D | ENSP00000398637 | ENSP00000287600 | ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasin [...] | 0.490 |
ARL16 | AMPH | ENSP00000380635 | ENSP00000348602 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. | 0.629 |
ARL16 | ARL10 | ENSP00000380635 | ENSP00000308496 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | ADP-ribosylation factor-like protein 10; ADP ribosylation factor like GTPase 10; Belongs to the small GTPase superfamily. Arf family. | 0.659 |
ARL16 | ARL11 | ENSP00000380635 | ENSP00000282026 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor. Belongs to the small GTPase superfamily. Arf family. | 0.558 |
ARL16 | ARL13A | ENSP00000380635 | ENSP00000398637 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | ADP-ribosylation factor-like protein 13A; ADP ribosylation factor like GTPase 13A. | 0.684 |
ARL16 | ARL4A | ENSP00000380635 | ENSP00000379898 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | ADP-ribosylation factor-like protein 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. | 0.526 |
ARL16 | ARL9 | ENSP00000380635 | ENSP00000492671 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9. | 0.718 |
ARL16 | CDKN2AIPNL | ENSP00000380635 | ENSP00000394183 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | CDKN2AIP N-terminal-like protein; CDKN2A interacting protein N-terminal like. | 0.519 |
ARL16 | PDE6D | ENSP00000380635 | ENSP00000287600 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasin [...] | 0.782 |
ARL16 | RNF125 | ENSP00000380635 | ENSP00000217740 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | E3 ubiquitin-protein ligase RNF125; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins, such as DDX58/RIG-I, MAVS/IPS1, IFIH1/MDA5, JAK1 and p53/TP53. Acts as a negative regulator of type I interferon production by mediating ubiquitination of DDX58/RIG-I at 'Lys-181', leading to DDX58/RIG-I degradation. Mediates ubiquitination and subsequent degradation of p53/TP53. Mediates ubiquitination and subsequent degradation of JAK1. Acts as a positive regulator of T-cell activation. | 0.530 |
ARL16 | SRPRB | ENSP00000380635 | ENSP00000418401 | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | Signal recognition particle receptor subunit beta; Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR (By similarity). | 0.505 |
ARL4A | ARL16 | ENSP00000379898 | ENSP00000380635 | ADP-ribosylation factor-like protein 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.526 |
ARL9 | ARL16 | ENSP00000492671 | ENSP00000380635 | ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.718 |
CDKN2AIPNL | ARL16 | ENSP00000394183 | ENSP00000380635 | CDKN2AIP N-terminal-like protein; CDKN2A interacting protein N-terminal like. | ADP-ribosylation factor-like protein 16; ADP ribosylation factor like GTPase 16. | 0.519 |