node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRIX1 | CEBPZ | ENSP00000338862 | ENSP00000234170 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | 0.954 |
BRIX1 | DDX18 | ENSP00000338862 | ENSP00000263239 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | 0.997 |
BRIX1 | EBNA1BP2 | ENSP00000338862 | ENSP00000407323 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.999 |
BRIX1 | FTSJ3 | ENSP00000338862 | ENSP00000396673 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.970 |
BRIX1 | GTPBP4 | ENSP00000338862 | ENSP00000354040 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. | 0.998 |
BRIX1 | NIFK | ENSP00000338862 | ENSP00000285814 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | Nucleolar protein interacting with the FHA domain of MKI67. | 0.999 |
BRIX1 | NOP2 | ENSP00000338862 | ENSP00000371858 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; Involved in ribosomal large subunit assembly. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.986 |
BRIX1 | PUM3 | ENSP00000338862 | ENSP00000380982 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity). | 0.988 |
BRIX1 | RBM28 | ENSP00000338862 | ENSP00000223073 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | RNA-binding protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes. | 0.948 |
BRIX1 | RPF2 | ENSP00000338862 | ENSP00000402338 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.993 |
CEBPZ | BRIX1 | ENSP00000234170 | ENSP00000338862 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. | 0.954 |
CEBPZ | DDX18 | ENSP00000234170 | ENSP00000263239 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | ATP-dependent RNA helicase DDX18; Probable RNA-dependent helicase; Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. | 0.958 |
CEBPZ | EBNA1BP2 | ENSP00000234170 | ENSP00000407323 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.968 |
CEBPZ | FTSJ3 | ENSP00000234170 | ENSP00000396673 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.929 |
CEBPZ | GTPBP4 | ENSP00000234170 | ENSP00000354040 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. | 0.983 |
CEBPZ | NIFK | ENSP00000234170 | ENSP00000285814 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Nucleolar protein interacting with the FHA domain of MKI67. | 0.951 |
CEBPZ | NOP2 | ENSP00000234170 | ENSP00000371858 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase; Involved in ribosomal large subunit assembly. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA (Probable). May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation (Probable); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.963 |
CEBPZ | PUM3 | ENSP00000234170 | ENSP00000380982 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Pumilio homolog 3; Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells (By similarity). | 0.972 |
CEBPZ | RBM28 | ENSP00000234170 | ENSP00000223073 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | RNA-binding protein 28; Nucleolar component of the spliceosomal ribonucleoprotein complexes. | 0.984 |
CEBPZ | RPF2 | ENSP00000234170 | ENSP00000402338 | CCAAT/enhancer-binding protein zeta; Stimulates transcription from the HSP70 promoter; Belongs to the CBF/MAK21 family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus. | 0.975 |