node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CXorf66 | DIPK2B | ENSP00000359571 | ENSP00000381086 | Uncharacterized protein CXorf66; Chromosome X open reading frame 66. | Divergent protein kinase domain 2B. | 0.506 |
DIPK1A | DIPK1B | ENSP00000359333 | ENSP00000360757 | Divergent protein kinase domain 1A. | Divergent protein kinase domain 1B; Belongs to the DIPK family. | 0.450 |
DIPK1A | DIPK2B | ENSP00000359333 | ENSP00000381086 | Divergent protein kinase domain 1A. | Divergent protein kinase domain 2B. | 0.657 |
DIPK1A | PKDCC | ENSP00000359333 | ENSP00000294964 | Divergent protein kinase domain 1A. | Extracellular tyrosine-protein kinase PKDCC; Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation [...] | 0.518 |
DIPK1A | POMK | ENSP00000359333 | ENSP00000331258 | Divergent protein kinase domain 1A. | Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...] | 0.446 |
DIPK1B | DIPK1A | ENSP00000360757 | ENSP00000359333 | Divergent protein kinase domain 1B; Belongs to the DIPK family. | Divergent protein kinase domain 1A. | 0.450 |
DIPK1B | DIPK2B | ENSP00000360757 | ENSP00000381086 | Divergent protein kinase domain 1B; Belongs to the DIPK family. | Divergent protein kinase domain 2B. | 0.573 |
DIPK1C | DIPK2B | ENSP00000344331 | ENSP00000381086 | Divergent protein kinase domain 1C. | Divergent protein kinase domain 2B. | 0.724 |
DIPK2B | CXorf66 | ENSP00000381086 | ENSP00000359571 | Divergent protein kinase domain 2B. | Uncharacterized protein CXorf66; Chromosome X open reading frame 66. | 0.506 |
DIPK2B | DIPK1A | ENSP00000381086 | ENSP00000359333 | Divergent protein kinase domain 2B. | Divergent protein kinase domain 1A. | 0.657 |
DIPK2B | DIPK1B | ENSP00000381086 | ENSP00000360757 | Divergent protein kinase domain 2B. | Divergent protein kinase domain 1B; Belongs to the DIPK family. | 0.573 |
DIPK2B | DIPK1C | ENSP00000381086 | ENSP00000344331 | Divergent protein kinase domain 2B. | Divergent protein kinase domain 1C. | 0.724 |
DIPK2B | DUSP21 | ENSP00000381086 | ENSP00000343244 | Divergent protein kinase domain 2B. | Dual specificity protein phosphatase 21; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. | 0.502 |
DIPK2B | LRATD2 | ENSP00000381086 | ENSP00000302578 | Divergent protein kinase domain 2B. | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | 0.428 |
DIPK2B | PKDCC | ENSP00000381086 | ENSP00000294964 | Divergent protein kinase domain 2B. | Extracellular tyrosine-protein kinase PKDCC; Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation [...] | 0.480 |
DIPK2B | POMK | ENSP00000381086 | ENSP00000331258 | Divergent protein kinase domain 2B. | Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)- beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4- (phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...] | 0.509 |
DIPK2B | RRP12 | ENSP00000381086 | ENSP00000446184 | Divergent protein kinase domain 2B. | RRP12-like protein; Ribosomal RNA processing 12 homolog. | 0.475 |
DIPK2B | TCEANC | ENSP00000381086 | ENSP00000440038 | Divergent protein kinase domain 2B. | Transcription elongation factor A N-terminal and central domain containing. | 0.429 |
DUSP21 | DIPK2B | ENSP00000343244 | ENSP00000381086 | Dual specificity protein phosphatase 21; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. | Divergent protein kinase domain 2B. | 0.502 |
LRATD2 | DIPK2B | ENSP00000302578 | ENSP00000381086 | Protein LRATD2; LRAT domain containing 2; Belongs to the LRATD family. | Divergent protein kinase domain 2B. | 0.428 |