| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACSF2 | MRPL11 | ENSP00000401831 | ENSP00000308897 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | 0.933 |
| ACSF2 | MRPL13 | ENSP00000401831 | ENSP00000306548 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | 0.937 |
| ACSF2 | MRPL3 | ENSP00000401831 | ENSP00000264995 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | Mitochondrial ribosomal protein L3. | 0.938 |
| ACSF2 | TMEM123 | ENSP00000401831 | ENSP00000381204 | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.439 |
| CFAP300 | TMEM123 | ENSP00000414390 | ENSP00000381204 | Cilia- and flagella-associated protein 300; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.467 |
| MRPL11 | ACSF2 | ENSP00000308897 | ENSP00000401831 | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | 0.933 |
| MRPL11 | MRPL13 | ENSP00000308897 | ENSP00000306548 | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | 0.999 |
| MRPL11 | MRPL3 | ENSP00000308897 | ENSP00000264995 | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | Mitochondrial ribosomal protein L3. | 0.997 |
| MRPL11 | TMEM123 | ENSP00000308897 | ENSP00000381204 | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.448 |
| MRPL13 | ACSF2 | ENSP00000306548 | ENSP00000401831 | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | 0.937 |
| MRPL13 | MRPL11 | ENSP00000306548 | ENSP00000308897 | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | 0.999 |
| MRPL13 | MRPL3 | ENSP00000306548 | ENSP00000264995 | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | Mitochondrial ribosomal protein L3. | 0.999 |
| MRPL13 | TMEM123 | ENSP00000306548 | ENSP00000381204 | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.473 |
| MRPL3 | ACSF2 | ENSP00000264995 | ENSP00000401831 | Mitochondrial ribosomal protein L3. | Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. | 0.938 |
| MRPL3 | MRPL11 | ENSP00000264995 | ENSP00000308897 | Mitochondrial ribosomal protein L3. | Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family. | 0.997 |
| MRPL3 | MRPL13 | ENSP00000264995 | ENSP00000306548 | Mitochondrial ribosomal protein L3. | Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. | 0.999 |
| MRPL3 | TMEM123 | ENSP00000264995 | ENSP00000381204 | Mitochondrial ribosomal protein L3. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.483 |
| PCNP | TMEM123 | ENSP00000265260 | ENSP00000381204 | PEST proteolytic signal-containing nuclear protein; May be involved in cell cycle regulation. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.444 |
| PSMC6 | TMEM123 | ENSP00000484998 | ENSP00000381204 | 26S proteasome regulatory subunit 10B; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated wi [...] | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.458 |
| SLC25A31 | TMEM123 | ENSP00000281154 | ENSP00000381204 | ADP/ATP translocase 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility. Belongs to the mitochondrial carrier (TC 2.A.29) family. | Porimin; Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. | 0.439 |