STRINGSTRING
GGT5 protein (human) - STRING interaction network
"GGT5" - Glutathione hydrolase 5 proenzyme in Homo sapiens
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GGT5Glutathione hydrolase 5 proenzyme; Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4); Belongs to the gamma-glutamyltransferase family (587 aa)    
Predicted Functional Partners:
OPLAH
5-oxoprolinase; Catalyzes the cleavage of 5-oxo-L-proline to form L- glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate (1288 aa)
   
 
  0.947
GSS
Glutathione synthetase; Belongs to the eukaryotic GSH synthase family (474 aa)
     
 
  0.946
DPEP2
Dipeptidase 2; Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) (486 aa)
   
 
  0.945
ANPEP
Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization; Aminopeptidases (967 aa)
     
 
  0.944
LAP3
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family (519 aa)
     
 
  0.933
GCLC
Glutamate-cysteine ligase catalytic subunit (637 aa)
     
 
  0.928
GSR
Glutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol (522 aa)
       
  0.927
DPEP1
Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity (411 aa)
   
 
  0.925
LTC4S
Leukotriene C4 synthase; Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4 (150 aa)
         
  0.921
GCLM
Glutamate-cysteine ligase modifier subunit; Belongs to the aldo/keto reductase family. Glutamate-- cysteine ligase light chain subfamily (274 aa)
     
 
  0.918
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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