STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS12Transmembrane serine protease 12; Belongs to the peptidase S1 family. (348 aa)    
Predicted Functional Partners:
RNF215
Ring finger protein 215.
   
  
 0.666
ERGIC2
Endoplasmic reticulum-Golgi intermediate compartment protein 2; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the ERGIC family.
      
 0.571
ZNF10
Zinc finger protein 10; May be involved in transcriptional regulation.
    
 
 0.545
TPPP2
Tubulin polymerization-promoting protein family member 2; Probable regulator of microtubule dynamics required for sperm motility (Probable). In contrast to other members of the family, has no microtubule bundling activity.
   
  
 0.507
FAM217A
Protein FAM217A; Family with sequence similarity 217 member A; Belongs to the FAM217 family.
   
  
 0.502
SPATA31D4
Spermatogenesis-associated protein 31D4; May play a role in spermatogenesis; Belongs to the SPATA31 family.
    
 
 0.502
FAM170B
Protein FAM170B; Plays a role in fertilization through the acrosome reaction. Belongs to the FAM170 family.
   
 
 0.474
TMPRSS11B
Transmembrane protease serine 11B; Serine protease.
  
  
0.472
SSMEM1
Serine rich single-pass membrane protein 1.
   
  
 0.451
OR6M1
Olfactory receptor 6M1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.442
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.