SMIM11A protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

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... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C17orf58	SMIM11A	ENSP00000402020	ENSP00000498771	UPF0450 protein C17orf58; Chromosome 17 open reading frame 58.	Small integral membrane protein 11A.	0.406
PAXBP1	SMIM11A	ENSP00000328992	ENSP00000498771	PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity); Belongs to the GCF family.	Small integral membrane protein 11A.	0.461
PAXBP1	TMEM50B	ENSP00000328992	ENSP00000439768	PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity); Belongs to the GCF family.	Transmembrane protein 50B; Belongs to the UPF0220 family.	0.522
SMIM11A	C17orf58	ENSP00000498771	ENSP00000402020	Small integral membrane protein 11A.	UPF0450 protein C17orf58; Chromosome 17 open reading frame 58.	0.406
SMIM11A	PAXBP1	ENSP00000498771	ENSP00000328992	Small integral membrane protein 11A.	PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity); Belongs to the GCF family.	0.461
SMIM11A	SMIM11B	ENSP00000498771	ENSP00000485484	Small integral membrane protein 11A.	Small integral membrane protein 11B; Belongs to the SMIM11 family.	0.921
SMIM11A	TMEM50B	ENSP00000498771	ENSP00000439768	Small integral membrane protein 11A.	Transmembrane protein 50B; Belongs to the UPF0220 family.	0.414
SMIM11B	SMIM11A	ENSP00000485484	ENSP00000498771	Small integral membrane protein 11B; Belongs to the SMIM11 family.	Small integral membrane protein 11A.	0.921
TMEM50B	PAXBP1	ENSP00000439768	ENSP00000328992	Transmembrane protein 50B; Belongs to the UPF0220 family.	PAX3- and PAX7-binding protein 1; Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity); Belongs to the GCF family.	0.522
TMEM50B	SMIM11A	ENSP00000439768	ENSP00000498771	Transmembrane protein 50B; Belongs to the UPF0220 family.	Small integral membrane protein 11A.	0.414