• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
N4BP2L2 protein (human) - STRING interaction network
"N4BP2L2" - NEDD4 binding protein 2 like 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N4BP2L2NEDD4 binding protein 2 like 2 (752 aa)    
Predicted Functional Partners:
PPIA
Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily (165 aa)
       
      0.723
LARP1B
La-related protein 1B; La ribonucleoprotein domain family member 1B; Belongs to the LARP family (914 aa)
     
   
  0.646
MAN1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2) (641 aa)
           
  0.603
UBAP2
Ubiquitin associated protein 2 (1119 aa)
           
  0.566
ZNF805
Zinc finger protein 805; May be involved in transcriptional regulation; Zinc fingers C2H2-type (627 aa)
           
  0.559
PHC3
Polyhomeotic-like protein 3; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ’Lys-119’, rendering chromatin heritably changed in its expressibility; Sterile alpha motif domain containing (995 aa)
     
   
  0.483
SUZ12
Polycomb protein SUZ12; Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates ’Lys-9’ (H3K9me) and ’Lys-27’ (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A (739 aa)
     
   
  0.473
ANKRD34A
Ankyrin repeat domain-containing protein 34A; Ankyrin repeat domain containing; Belongs to the ANKRD34 family (496 aa)
           
  0.461
PDE4DIP
Myomegalin; Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes (By similarity). Forms a complex with AKAP9- the complex recruits CAMSAP2 to the Golgi apparatus, leading to tether non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (2362 aa)
       
 
  0.456
FAM69B
Protein FAM69B; Family with sequence similarity 69 member B; Belongs to the FAM69 family (431 aa)
           
  0.456
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (19%) [HD]