STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MROH2BMaestro heat-like repeat-containing protein family member 2B; May play a role in the process of sperm capacitation. (1585 aa)    
Predicted Functional Partners:
IL7R
Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP); Belongs to the type I cytokine receptor family. Type 4 subfamily.
      
 0.675
MROH7
Maestro heat like repeat family member 7.
  
   
0.507
MROH2A
Maestro heat like repeat family member 2A.
  
   
0.462
MB21D2
Protein MB21D2; Mab-21 domain containing 2.
      
 0.451
BAG3
BAG family molecular chaperone regulator 3; Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. Has anti- apoptotic activity. Plays a role in the HSF1 nucleocytoplasmic transport.
   
  
 0.446
CCDC105
Coiled-coil domain containing 105.
   
  
 0.444
BANF2
Barrier-to-autointegration factor-like protein; May play a role in BANF1 regulation and influence tissue- specific roles of BANF1; Belongs to the BAF family.
   
    0.437
MROH9
Maestro heat like repeat family member 9.
   
  
0.426
MROH1
Maestro heat like repeat family member 1.
  
   
0.422
OR10A7
Olfactory receptor 10A7; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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