TSSK2 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP3	ARMC12	ENSP00000228850	ENSP00000288065	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Armadillo repeat containing 12.	0.770
AKAP3	C7orf31	ENSP00000228850	ENSP00000283905	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.616
AKAP3	CCIN	ENSP00000228850	ENSP00000334996	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	0.884
AKAP3	FAM166A	ENSP00000228850	ENSP00000344729	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Protein FAM166A; Family with sequence similarity 166 member A.	0.730
AKAP3	TEKT4	ENSP00000228850	ENSP00000295201	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family.	0.842
AKAP3	TSKS	ENSP00000228850	ENSP00000246801	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Testis-specific serine kinase substrate; May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.	0.480
AKAP3	TSSK1B	ENSP00000228850	ENSP00000375081	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Testis-specific serine/threonine-protein kinase 1; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.	0.635
AKAP3	TSSK2	ENSP00000228850	ENSP00000382544	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	Testis-specific serine/threonine-protein kinase 2; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.	0.643
ARMC12	AKAP3	ENSP00000288065	ENSP00000228850	Armadillo repeat containing 12.	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	0.770
ARMC12	CCIN	ENSP00000288065	ENSP00000334996	Armadillo repeat containing 12.	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	0.654
ARMC12	FAM166A	ENSP00000288065	ENSP00000344729	Armadillo repeat containing 12.	Protein FAM166A; Family with sequence similarity 166 member A.	0.741
ARMC12	TEKT4	ENSP00000288065	ENSP00000295201	Armadillo repeat containing 12.	Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family.	0.591
ARMC12	TSSK1B	ENSP00000288065	ENSP00000375081	Armadillo repeat containing 12.	Testis-specific serine/threonine-protein kinase 1; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.	0.566
ARMC12	TSSK2	ENSP00000288065	ENSP00000382544	Armadillo repeat containing 12.	Testis-specific serine/threonine-protein kinase 2; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates TSKS at 'Ser-288' and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.	0.652
C7orf31	AKAP3	ENSP00000283905	ENSP00000228850	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	A-kinase anchor protein 3; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction.	0.616
C7orf31	CCIN	ENSP00000283905	ENSP00000334996	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	0.863
C7orf31	FAM166A	ENSP00000283905	ENSP00000344729	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Protein FAM166A; Family with sequence similarity 166 member A.	0.834
C7orf31	TEKT4	ENSP00000283905	ENSP00000295201	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family.	0.823
C7orf31	TSKS	ENSP00000283905	ENSP00000246801	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Testis-specific serine kinase substrate; May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.	0.401
C7orf31	TSSK1B	ENSP00000283905	ENSP00000375081	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Testis-specific serine/threonine-protein kinase 1; Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body.	0.402