STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTRNR2L4Humanin-like 4; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family. (28 aa)    
Predicted Functional Partners:
MTRNR2L6
Humanin-like 6; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
   
  
 0.929
MTRNR2L5
Humanin-like 5; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
   
  
 0.800
MTRNR2L10
Humanin-like 10; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
   
    0.764
MTRNR2L13
Humanin-like 13; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
   
  
 0.747
MTRNR2L7
Humanin-like 7; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
   
  
 0.742
MTRNR2L8
Humanin-like 8; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
   
  
 0.670
MARVELD1
MARVEL domain-containing protein 1; Microtubule-associated protein that exhibits cell cycle- dependent localization and can inhibit cell proliferation and migration.
      
 0.609
MAU2
MAU2 chromatid cohesion factor homolog; Plays an important role in the loading of the cohesin complex on to DNA. Forms a heterodimeric complex (also known as cohesin loading complex) with NIPBL/SCC2 which mediates the loading of the cohesin complex onto chromatin. Plays a role in sister chromatid cohesion and normal progression through prometaphase.
      
 0.600
LIPN
Lipase member N; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.
      
 0.593
CADM1
Cell adhesion molecule 1; Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attach [...]
      
 0.435
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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