node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DEFB103A | DEFB106B | ENSP00000320951 | ENSP00000334364 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | 0.927 |
DEFB103A | DEFB107A | ENSP00000320951 | ENSP00000334681 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 107; Has antibacterial activity. | 0.879 |
DEFB103A | DEFB118 | ENSP00000320951 | ENSP00000253381 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 118; Has antibacterial activity. | 0.685 |
DEFB103A | DEFB119 | ENSP00000320951 | ENSP00000365492 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Defensin beta 119. | 0.575 |
DEFB103A | DEFB125 | ENSP00000320951 | ENSP00000371847 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. | 0.499 |
DEFB103A | DEFB126 | ENSP00000320951 | ENSP00000371835 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...] | 0.696 |
DEFB103A | DEFB130A | ENSP00000320951 | ENSP00000382951 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity. | 0.684 |
DEFB103A | DEFB131A | ENSP00000320951 | ENSP00000335538 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 131A; Has antibacterial activity (Probable). Upon stimulation with lipoteichoic acid, promotes cytokines and chemokines production and secretion ; Belongs to the beta-defensin family. | 0.607 |
DEFB103A | DEFB135 | ENSP00000320951 | ENSP00000371643 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family. | 0.549 |
DEFB103A | DEFB136 | ENSP00000320951 | ENSP00000371644 | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family. | 0.499 |
DEFB106B | DEFB103A | ENSP00000334364 | ENSP00000320951 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | 0.927 |
DEFB106B | DEFB107A | ENSP00000334364 | ENSP00000334681 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 107; Has antibacterial activity. | 0.936 |
DEFB106B | DEFB118 | ENSP00000334364 | ENSP00000253381 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 118; Has antibacterial activity. | 0.750 |
DEFB106B | DEFB119 | ENSP00000334364 | ENSP00000365492 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Defensin beta 119. | 0.734 |
DEFB106B | DEFB125 | ENSP00000334364 | ENSP00000371847 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family. | 0.637 |
DEFB106B | DEFB126 | ENSP00000334364 | ENSP00000371835 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 126; Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other s [...] | 0.802 |
DEFB106B | DEFB130A | ENSP00000334364 | ENSP00000382951 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity. | 0.622 |
DEFB106B | DEFB131A | ENSP00000334364 | ENSP00000335538 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 131A; Has antibacterial activity (Probable). Upon stimulation with lipoteichoic acid, promotes cytokines and chemokines production and secretion ; Belongs to the beta-defensin family. | 0.577 |
DEFB106B | DEFB135 | ENSP00000334364 | ENSP00000371643 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family. | 0.521 |
DEFB106B | DEFB136 | ENSP00000334364 | ENSP00000371644 | Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family. | Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family. | 0.516 |