STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM72DProtein FAM72D; Family with sequence similarity 72 member D (149 aa)    
Predicted Functional Partners:
CBWD7
COBW domain-containing protein 6; COBW domain containing 7; Belongs to the SIMIBI class G3E GTPase family. CobW subfamily
      
 0.634
ANKRD20A2
Ankyrin repeat domain-containing protein 20A2; Ankyrin repeat domain 20 family member A2
      
 0.633
ANKRD20A4
Ankyrin repeat domain-containing protein 20A4; Ankyrin repeat domain 20 family member A4
      
 0.632
ARHGAP11B
Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity; Rho GTPase activating proteins
   
  
 0.591
ANKRD20A1
Ankyrin repeat domain-containing protein 20A1; Ankyrin repeat domain 20 family member A1
      
 0.590
ARHGAP11A
Rho GTPase activating protein 11A
   
  
 0.572
FAM182B
Protein FAM182B; Family with sequence similarity 182 member B
      
 0.527
ZNF492
Zinc finger protein 492; May be involved in transcriptional regulation; Zinc fingers C2H2-type
      
 0.527
TTK
Dual specificity protein kinase TTK; Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint
   
  
 0.507
SRGAP2B
SLIT-ROBO Rho GTPase-activating protein 2B; May regulate cell migration and differentiation through interaction with and inhibition of SRGAP2; F-BAR domain containing
      
 0.499
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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