STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC34Tetratricopeptide repeat domain 34. (566 aa)    
Predicted Functional Partners:
C2orf81
Uncharacterized protein C2orf81; Chromosome 2 open reading frame 81.
   
  
 0.604
IQCE
IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis.
   
    0.594
KIAA1958
Uncharacterized protein KIAA1958; KIAA1958.
   
  
 0.538
FHAD1
Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.
      
 0.483
SPDYE3
Speedy protein E3; speedy/RINGO cell cycle regulator family member E3.
      
 0.445
PRSS36
Polyserase-2; Serine protease. Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg- AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala- Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a preference for substrates with an Arg instead of a Lys residue in position P1; Belongs to the peptidase S1 family.
   
 
 0.430
TCP10L2
T-complex protein 10A homolog 2; T-complex 10 like 2, pseudogene; Belongs to the TCP10 family.
   
  
 0.425
ZNF385B
Zinc finger protein 385B; May play a role in p53/TP53-mediated apoptosis.
    
 
 0.403
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.