| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DMRT3 | DMRTA2 | ENSP00000190165 | ENSP00000383909 | Doublesex- and mab-3-related transcription factor 3; Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity); Belongs to the DMRT family. | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.444 |
| DMRT3 | EMX2 | ENSP00000190165 | ENSP00000450962 | Doublesex- and mab-3-related transcription factor 3; Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity); Belongs to the DMRT family. | Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. | 0.511 |
| DMRTA2 | DMRT3 | ENSP00000383909 | ENSP00000190165 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Doublesex- and mab-3-related transcription factor 3; Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity); Belongs to the DMRT family. | 0.444 |
| DMRTA2 | EMX1 | ENSP00000383909 | ENSP00000258106 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Homeobox protein EMX1; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. | 0.417 |
| DMRTA2 | EMX2 | ENSP00000383909 | ENSP00000450962 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. | 0.540 |
| DMRTA2 | FAF1 | ENSP00000383909 | ENSP00000379457 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | FAS-associated factor 1; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis (By similarity). | 0.445 |
| DMRTA2 | FOXL1 | ENSP00000383909 | ENSP00000326272 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Forkhead box protein L1; Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity). | 0.509 |
| DMRTA2 | FOXL3 | ENSP00000383909 | ENSP00000492766 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Fork-head domain-containing protein. | 0.411 |
| DMRTA2 | HMBOX1 | ENSP00000383909 | ENSP00000430110 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Homeobox-containing protein 1; Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA. Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation. Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres (By similarity). Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs). Enhances formation of telomere C-circles i [...] | 0.453 |
| DMRTA2 | LMX1A | ENSP00000383909 | ENSP00000340226 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). | 0.430 |
| DMRTA2 | NFIA | ENSP00000383909 | ENSP00000360231 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | Nuclear factor 1 A-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.513 |
| DMRTA2 | SLC18B1 | ENSP00000383909 | ENSP00000275227 | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | MFS-type transporter SLC18B1; Solute carrier family 18 member B1. | 0.444 |
| EMX1 | DMRTA2 | ENSP00000258106 | ENSP00000383909 | Homeobox protein EMX1; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.417 |
| EMX2 | DMRT3 | ENSP00000450962 | ENSP00000190165 | Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. | Doublesex- and mab-3-related transcription factor 3; Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development (By similarity); Belongs to the DMRT family. | 0.511 |
| EMX2 | DMRTA2 | ENSP00000450962 | ENSP00000383909 | Homeobox protein EMX2; Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.540 |
| FAF1 | DMRTA2 | ENSP00000379457 | ENSP00000383909 | FAS-associated factor 1; Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis (By similarity). | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.445 |
| FOXL1 | DMRTA2 | ENSP00000326272 | ENSP00000383909 | Forkhead box protein L1; Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity). | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.509 |
| FOXL3 | DMRTA2 | ENSP00000492766 | ENSP00000383909 | Fork-head domain-containing protein. | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.411 |
| HMBOX1 | DMRTA2 | ENSP00000430110 | ENSP00000383909 | Homeobox-containing protein 1; Binds directly to 5'-TTAGGG-3' repeats in telomeric DNA. Associates with the telomerase complex at sites of active telomere processing and positively regulates telomere elongation. Important for TERT binding to chromatin, indicating a role in recruitment of the telomerase complex to telomeres (By similarity). Also plays a role in the alternative lengthening of telomeres (ALT) pathway in telomerase-negative cells where it promotes formation and/or maintenance of ALT-associated promyelocytic leukemia bodies (APBs). Enhances formation of telomere C-circles i [...] | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.453 |
| LMX1A | DMRTA2 | ENSP00000340226 | ENSP00000383909 | LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae (By similarity). | Doublesex- and mab-3-related transcription factor A2; May be involved in sexual development. | 0.430 |