node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNPY1 | RBM33 | ENSP00000317439 | ENSP00000384160 | Canopy FGF signaling regulator 1; Belongs to the canopy family. | RNA binding motif protein 33. | 0.541 |
EME1 | RBM33 | ENSP00000376952 | ENSP00000384160 | Crossover junction endonuclease EME1; Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. Belongs to the EME1/MMS4 family. | RNA binding motif protein 33. | 0.583 |
FAM83C | RBM33 | ENSP00000363529 | ENSP00000384160 | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | RNA binding motif protein 33. | 0.506 |
FGGY | RBM33 | ENSP00000360262 | ENSP00000384160 | FGGY carbohydrate kinase domain containing; Belongs to the FGGY kinase family. | RNA binding motif protein 33. | 0.510 |
FGGY | USP24 | ENSP00000360262 | ENSP00000294383 | FGGY carbohydrate kinase domain containing; Belongs to the FGGY kinase family. | Ubiquitin carboxyl-terminal hydrolase 24; Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in lysosomes and releases free iron. | 0.412 |
LMBR1 | NOM1 | ENSP00000326604 | ENSP00000275820 | Limb region 1 protein homolog; Putative membrane receptor. | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | 0.737 |
LMBR1 | RBM33 | ENSP00000326604 | ENSP00000384160 | Limb region 1 protein homolog; Putative membrane receptor. | RNA binding motif protein 33. | 0.554 |
LMBR1 | RNF32 | ENSP00000326604 | ENSP00000385285 | Limb region 1 protein homolog; Putative membrane receptor. | RING finger protein 32; May play a role in sperm formation. | 0.799 |
NCBP3 | NOM1 | ENSP00000373657 | ENSP00000275820 | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | 0.571 |
NCBP3 | RBM33 | ENSP00000373657 | ENSP00000384160 | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | RNA binding motif protein 33. | 0.609 |
NCBP3 | THOC7 | ENSP00000373657 | ENSP00000295899 | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | THO complex subunit 7 homolog; Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre- mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm v [...] | 0.747 |
NOM1 | LMBR1 | ENSP00000275820 | ENSP00000326604 | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | Limb region 1 protein homolog; Putative membrane receptor. | 0.737 |
NOM1 | NCBP3 | ENSP00000275820 | ENSP00000373657 | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | Nuclear cap-binding protein subunit 3; Associates with NCBP1/CBP80 to form an alternative cap- binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress [...] | 0.571 |
NOM1 | RBM33 | ENSP00000275820 | ENSP00000384160 | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | RNA binding motif protein 33. | 0.659 |
NOM1 | RNF32 | ENSP00000275820 | ENSP00000385285 | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | RING finger protein 32; May play a role in sperm formation. | 0.775 |
RBM33 | CNPY1 | ENSP00000384160 | ENSP00000317439 | RNA binding motif protein 33. | Canopy FGF signaling regulator 1; Belongs to the canopy family. | 0.541 |
RBM33 | EME1 | ENSP00000384160 | ENSP00000376952 | RNA binding motif protein 33. | Crossover junction endonuclease EME1; Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. Belongs to the EME1/MMS4 family. | 0.583 |
RBM33 | FAM83C | ENSP00000384160 | ENSP00000363529 | RNA binding motif protein 33. | Protein FAM83C; May play a role in MAPK signaling. Belongs to the FAM83 family. | 0.506 |
RBM33 | FGGY | ENSP00000384160 | ENSP00000360262 | RNA binding motif protein 33. | FGGY carbohydrate kinase domain containing; Belongs to the FGGY kinase family. | 0.510 |
RBM33 | LMBR1 | ENSP00000384160 | ENSP00000326604 | RNA binding motif protein 33. | Limb region 1 protein homolog; Putative membrane receptor. | 0.554 |