STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEBPZOSProtein CEBPZOS; CEBPZ opposite strand. (80 aa)    
Predicted Functional Partners:
C16orf58
RUS1 family protein C16orf58.
      
 0.608
FAM214B
Protein FAM214B; Family with sequence similarity 214 member B; Belongs to the FAM214 family.
      
 0.585
MTRES1
Mitochondrial transcription rescue factor 1; Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability.
      
 0.522
CCDC127
Coiled-coil domain containing 127.
   
  
 0.509
COA7
Cytochrome c oxidase assembly factor 7; Required for assembly of mitochondrial respiratory chain complex I and complex IV; Belongs to the hcp beta-lactamase family.
   
  
 0.469
EXOG
Nuclease EXOG, mitochondrial; Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
      
 0.461
SAMD4B
Protein Smaug homolog 2; Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A. Belongs to the SMAUG family.
   
  
 0.457
RPP14
Ribonuclease P protein subunit p14; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
   
    0.443
FXYD4
FXYD domain containing ion transport regulator 4.
      
 0.422
METTL7A
Methyltransferase-like protein 7A; Probable methyltransferase.
   
  
 0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.