STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC157Coiled-coil domain containing 157. (752 aa)    
Predicted Functional Partners:
SERPINE3
Serpin E3; Probable serine protease inhibitor.
   
    0.594
RNF215
Ring finger protein 215.
  
  
 0.547
FAM124A
Protein FAM124A; Family with sequence similarity 124 member A; Belongs to the FAM124 family.
   
    0.461
FAM124B
Protein FAM124B; Family with sequence similarity 124 member B; Belongs to the FAM124 family.
   
    0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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