ANKMY1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

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gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKMY1	CFAP20	ENSP00000385887	ENSP00000262498	Ankyrin repeat and MYND domain containing 1.	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	0.656
ANKMY1	CFAP70	ENSP00000385887	ENSP00000310829	Ankyrin repeat and MYND domain containing 1.	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	0.641
ANKMY1	DLEC1	ENSP00000385887	ENSP00000308597	Ankyrin repeat and MYND domain containing 1.	Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.	0.641
ANKMY1	DPY30	ENSP00000385887	ENSP00000345837	Ankyrin repeat and MYND domain containing 1.	Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family.	0.648
ANKMY1	GOT1L1	ENSP00000385887	ENSP00000303077	Ankyrin repeat and MYND domain containing 1.	Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1.	0.645
ANKMY1	KIF9	ENSP00000385887	ENSP00000333942	Ankyrin repeat and MYND domain containing 1.	Kinesin-like protein KIF9; Kinesin family member 9.	0.641
ANKMY1	LRGUK	ENSP00000385887	ENSP00000285928	Ankyrin repeat and MYND domain containing 1.	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.	0.641
ANKMY1	MAP1S	ENSP00000385887	ENSP00000325313	Ankyrin repeat and MYND domain containing 1.	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family.	0.641
ANKMY1	SPATA17	ENSP00000385887	ENSP00000355900	Ankyrin repeat and MYND domain containing 1.	Spermatogenesis-associated protein 17; Spermatogenesis associated 17.	0.642
ANKMY1	SPATA4	ENSP00000385887	ENSP00000280191	Ankyrin repeat and MYND domain containing 1.	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.646
CFAP20	ANKMY1	ENSP00000262498	ENSP00000385887	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Ankyrin repeat and MYND domain containing 1.	0.656
CFAP20	CFAP70	ENSP00000262498	ENSP00000310829	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	0.677
CFAP20	DLEC1	ENSP00000262498	ENSP00000308597	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.	0.642
CFAP20	DPY30	ENSP00000262498	ENSP00000345837	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family.	0.641
CFAP20	GOT1L1	ENSP00000262498	ENSP00000303077	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1.	0.641
CFAP20	KIF9	ENSP00000262498	ENSP00000333942	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Kinesin-like protein KIF9; Kinesin family member 9.	0.641
CFAP20	LRGUK	ENSP00000262498	ENSP00000285928	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.	0.641
CFAP20	MAP1S	ENSP00000262498	ENSP00000325313	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family.	0.641
CFAP20	SPATA17	ENSP00000262498	ENSP00000355900	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Spermatogenesis-associated protein 17; Spermatogenesis associated 17.	0.641
CFAP20	SPATA4	ENSP00000262498	ENSP00000280191	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.641