TEX33 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATE1	TEX33	ENSP00000224652	ENSP00000386118	Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).	Testis-expressed protein 33; Testis expressed 33.	0.625
ATE1	UBR2	ENSP00000224652	ENSP00000361990	Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).	E3 ubiquitin-protein ligase UBR2; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. Required for spermatogenesis, promotes, w [...]	0.838
C10orf82	LYZL6	ENSP00000465712	ENSP00000483897	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.	0.500
C10orf82	SCP2D1	ENSP00000465712	ENSP00000366645	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1.	0.526
C10orf82	TEX33	ENSP00000465712	ENSP00000386118	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Testis-expressed protein 33; Testis expressed 33.	0.635
CARM1	TEX33	ENSP00000325690	ENSP00000386118	Histone-arginine methyltransferase CARM1; Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activa [...]	Testis-expressed protein 33; Testis expressed 33.	0.632
CCER1	MORN5	ENSP00000351727	ENSP00000362869	Coiled-coil glutamate rich protein 1.	MORN repeat containing 5.	0.610
CCER1	TEX33	ENSP00000351727	ENSP00000386118	Coiled-coil glutamate rich protein 1.	Testis-expressed protein 33; Testis expressed 33.	0.687
LRRK1	TEX33	ENSP00000373600	ENSP00000386118	Leucine rich repeat kinase 1; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.	Testis-expressed protein 33; Testis expressed 33.	0.771
LYZL6	C10orf82	ENSP00000483897	ENSP00000465712	Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	0.500
LYZL6	SCP2D1	ENSP00000483897	ENSP00000366645	Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1.	0.592
LYZL6	TEX33	ENSP00000483897	ENSP00000386118	Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.	Testis-expressed protein 33; Testis expressed 33.	0.585
MAN2C1	TEX33	ENSP00000457788	ENSP00000386118	Alpha-mannosidase 2C1; Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm; Belongs to the glycosyl hydrolase 38 family.	Testis-expressed protein 33; Testis expressed 33.	0.659
MORN5	CCER1	ENSP00000362869	ENSP00000351727	MORN repeat containing 5.	Coiled-coil glutamate rich protein 1.	0.610
MORN5	TEX33	ENSP00000362869	ENSP00000386118	MORN repeat containing 5.	Testis-expressed protein 33; Testis expressed 33.	0.592
SCP2D1	C10orf82	ENSP00000366645	ENSP00000465712	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1.	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	0.526
SCP2D1	LYZL6	ENSP00000366645	ENSP00000483897	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1.	Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.	0.592
SCP2D1	TEX33	ENSP00000366645	ENSP00000386118	SCP2 sterol-binding domain-containing protein 1; SCP2 sterol binding domain containing 1.	Testis-expressed protein 33; Testis expressed 33.	0.593
TEX33	ATE1	ENSP00000386118	ENSP00000224652	Testis-expressed protein 33; Testis expressed 33.	Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).	0.625
TEX33	C10orf82	ENSP00000386118	ENSP00000465712	Testis-expressed protein 33; Testis expressed 33.	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	0.635