| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DIPK1C | KLHL30 | ENSP00000344331 | ENSP00000386389 | Divergent protein kinase domain 1C. | Kelch-like protein 30; Kelch like family member 30. | 0.465 |
| EFCAB2 | KLHL30 | ENSP00000355480 | ENSP00000386389 | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC8 family. | Kelch-like protein 30; Kelch like family member 30. | 0.442 |
| KLHL30 | DIPK1C | ENSP00000386389 | ENSP00000344331 | Kelch-like protein 30; Kelch like family member 30. | Divergent protein kinase domain 1C. | 0.465 |
| KLHL30 | EFCAB2 | ENSP00000386389 | ENSP00000355480 | Kelch-like protein 30; Kelch like family member 30. | Dynein regulatory complex protein 8; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC8 family. | 0.442 |
| KLHL30 | KLHL31 | ENSP00000386389 | ENSP00000359942 | Kelch-like protein 30; Kelch like family member 30. | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | 0.417 |
| KLHL30 | KLHL40 | ENSP00000386389 | ENSP00000287777 | Kelch-like protein 30; Kelch like family member 30. | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | 0.431 |
| KLHL30 | METTL8 | ENSP00000386389 | ENSP00000480056 | Kelch-like protein 30; Kelch like family member 30. | mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs. | 0.462 |
| KLHL30 | NANP | ENSP00000386389 | ENSP00000302441 | Kelch-like protein 30; Kelch like family member 30. | N-acylneuraminate-9-phosphatase; N-acetylneuraminic acid phosphatase. | 0.555 |
| KLHL30 | NIF3L1 | ENSP00000386389 | ENSP00000498853 | Kelch-like protein 30; Kelch like family member 30. | NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. | 0.538 |
| KLHL30 | PRPF40A | ENSP00000386389 | ENSP00000386458 | Kelch-like protein 30; Kelch like family member 30. | Pre-mRNA-processing factor 40 homolog A; Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing; Belongs to the PRPF40 family. | 0.444 |
| KLHL30 | SUSD4 | ENSP00000386389 | ENSP00000344219 | Kelch-like protein 30; Kelch like family member 30. | Sushi domain-containing protein 4; Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways. | 0.443 |
| KLHL30 | WDR33 | ENSP00000386389 | ENSP00000325377 | Kelch-like protein 30; Kelch like family member 30. | pre-mRNA 3' end processing protein WDR33; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends. | 0.453 |
| KLHL31 | KLHL30 | ENSP00000359942 | ENSP00000386389 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | Kelch-like protein 30; Kelch like family member 30. | 0.417 |
| KLHL31 | KLHL40 | ENSP00000359942 | ENSP00000287777 | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | 0.498 |
| KLHL40 | KLHL30 | ENSP00000287777 | ENSP00000386389 | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | Kelch-like protein 30; Kelch like family member 30. | 0.431 |
| KLHL40 | KLHL31 | ENSP00000287777 | ENSP00000359942 | Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity). | Kelch-like protein 31; Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions. Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE). | 0.498 |
| METTL8 | KLHL30 | ENSP00000480056 | ENSP00000386389 | mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs. | Kelch-like protein 30; Kelch like family member 30. | 0.462 |
| METTL8 | NIF3L1 | ENSP00000480056 | ENSP00000498853 | mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs. | NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. | 0.421 |
| METTL8 | PRPF40A | ENSP00000480056 | ENSP00000386458 | mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs. | Pre-mRNA-processing factor 40 homolog A; Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing; Belongs to the PRPF40 family. | 0.427 |
| METTL8 | WDR33 | ENSP00000480056 | ENSP00000325377 | mRNA N(3)-methylcytidine methyltransferase METTL8; S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of mRNAs. | pre-mRNA 3' end processing protein WDR33; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends. | 0.421 |