node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYSRT1 | KPRP | ENSP00000386453 | ENSP00000475216 | Cysteine rich tail 1. | Keratinocyte proline rich protein. | 0.657 |
CYSRT1 | KRT78 | ENSP00000386453 | ENSP00000306261 | Cysteine rich tail 1. | Keratin, type II cytoskeletal 78; Keratin 78; Belongs to the intermediate filament family. | 0.642 |
CYSRT1 | KRTAP1-3 | ENSP00000386453 | ENSP00000344420 | Cysteine rich tail 1. | Keratin-associated protein 1-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.624 |
CYSRT1 | KRTAP9-8 | ENSP00000386453 | ENSP00000254072 | Cysteine rich tail 1. | Keratin-associated protein 9-8; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.592 |
CYSRT1 | LCE3A | ENSP00000386453 | ENSP00000335006 | Cysteine rich tail 1. | Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family. | 0.617 |
CYSRT1 | PLLP | ENSP00000386453 | ENSP00000219207 | Cysteine rich tail 1. | Plasmolipin; Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective (By similarity); Belongs to the MAL family. | 0.591 |
CYSRT1 | PRKAB2 | ENSP00000386453 | ENSP00000254101 | Cysteine rich tail 1. | 5'-AMP-activated protein kinase subunit beta-2; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a reg [...] | 0.591 |
CYSRT1 | SMIM5 | ENSP00000386453 | ENSP00000477017 | Cysteine rich tail 1. | Small integral membrane protein 5. | 0.593 |
CYSRT1 | WDR25 | ENSP00000386453 | ENSP00000334148 | Cysteine rich tail 1. | WD repeat domain 25. | 0.591 |
CYSRT1 | ZNF587 | ENSP00000386453 | ENSP00000345479 | Cysteine rich tail 1. | Zinc finger protein 587; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.603 |
KPRP | CYSRT1 | ENSP00000475216 | ENSP00000386453 | Keratinocyte proline rich protein. | Cysteine rich tail 1. | 0.657 |
KPRP | KRT78 | ENSP00000475216 | ENSP00000306261 | Keratinocyte proline rich protein. | Keratin, type II cytoskeletal 78; Keratin 78; Belongs to the intermediate filament family. | 0.791 |
KPRP | LCE3A | ENSP00000475216 | ENSP00000335006 | Keratinocyte proline rich protein. | Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family. | 0.417 |
KRT78 | CYSRT1 | ENSP00000306261 | ENSP00000386453 | Keratin, type II cytoskeletal 78; Keratin 78; Belongs to the intermediate filament family. | Cysteine rich tail 1. | 0.642 |
KRT78 | KPRP | ENSP00000306261 | ENSP00000475216 | Keratin, type II cytoskeletal 78; Keratin 78; Belongs to the intermediate filament family. | Keratinocyte proline rich protein. | 0.791 |
KRTAP1-3 | CYSRT1 | ENSP00000344420 | ENSP00000386453 | Keratin-associated protein 1-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | Cysteine rich tail 1. | 0.624 |
KRTAP1-3 | KRTAP9-8 | ENSP00000344420 | ENSP00000254072 | Keratin-associated protein 1-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | Keratin-associated protein 9-8; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.730 |
KRTAP9-8 | CYSRT1 | ENSP00000254072 | ENSP00000386453 | Keratin-associated protein 9-8; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | Cysteine rich tail 1. | 0.592 |
KRTAP9-8 | KRTAP1-3 | ENSP00000254072 | ENSP00000344420 | Keratin-associated protein 9-8; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | Keratin-associated protein 1-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.730 |
LCE3A | CYSRT1 | ENSP00000335006 | ENSP00000386453 | Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family. | Cysteine rich tail 1. | 0.617 |