STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C7orf31Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31. (590 aa)    
Predicted Functional Partners:
LRCOL1
Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.
      
 0.705
C4orf47
UPF0602 protein C4orf47; Chromosome 4 open reading frame 47; Belongs to the UPF0602 family.
   
  
 0.694
CCDC96
Coiled-coil domain containing 96.
   
  
 0.653
FAM229B
Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.
      
 0.613
KLHL40
Kelch-like protein 40; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity).
   
   0.612
C10orf120
Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.
      
 0.606
CCDC38
Coiled-coil domain containing 38.
      
 0.584
CCDC116
Coiled-coil domain containing 116.
      
 0.583
CCDC113
Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.
   
  
 0.572
C10orf53
UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.
      
 0.571
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.