node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DDX27 | EPM2AIP1 | ENSP00000483495 | ENSP00000406027 | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | EPM2A interacting protein 1. | 0.444 |
DDX27 | LYG1 | ENSP00000483495 | ENSP00000386923 | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | Lysozyme g1. | 0.474 |
DDX27 | RPL22L1 | ENSP00000483495 | ENSP00000346080 | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | Ribosomal protein L22 like 1; Belongs to the eukaryotic ribosomal protein eL22 family. | 0.448 |
DDX27 | RTF2 | ENSP00000483495 | ENSP00000023939 | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | Replication termination factor 2; Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA ; Belongs to the rtf2 family. | 0.430 |
DDX27 | TTC30A | ENSP00000483495 | ENSP00000347915 | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | Tetratricopeptide repeat protein 30A; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip; Belongs to the TTC30/dfy-1/fleer family. | 0.420 |
DDX27 | ZSWIM3 | ENSP00000483495 | ENSP00000255152 | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | Zinc finger SWIM-type containing 3. | 0.469 |
EPM2AIP1 | DDX27 | ENSP00000406027 | ENSP00000483495 | EPM2A interacting protein 1. | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | 0.444 |
EPM2AIP1 | HENMT1 | ENSP00000406027 | ENSP00000359049 | EPM2A interacting protein 1. | Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. | 0.420 |
EPM2AIP1 | LYG1 | ENSP00000406027 | ENSP00000386923 | EPM2A interacting protein 1. | Lysozyme g1. | 0.572 |
EPM2AIP1 | RPL22L1 | ENSP00000406027 | ENSP00000346080 | EPM2A interacting protein 1. | Ribosomal protein L22 like 1; Belongs to the eukaryotic ribosomal protein eL22 family. | 0.440 |
EPM2AIP1 | RTF2 | ENSP00000406027 | ENSP00000023939 | EPM2A interacting protein 1. | Replication termination factor 2; Replication termination factor which is a component of the elongating replisome (Probable). Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion (Probable). Interacts with nascent DNA ; Belongs to the rtf2 family. | 0.456 |
EPM2AIP1 | SHROOM4 | ENSP00000406027 | ENSP00000365188 | EPM2A interacting protein 1. | Protein Shroom4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity); Belongs to the shroom family. | 0.475 |
EPM2AIP1 | SMAP1 | ENSP00000406027 | ENSP00000359484 | EPM2A interacting protein 1. | Stromal membrane-associated protein 1; GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis (By similarity). | 0.433 |
EPM2AIP1 | TTC30A | ENSP00000406027 | ENSP00000347915 | EPM2A interacting protein 1. | Tetratricopeptide repeat protein 30A; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip; Belongs to the TTC30/dfy-1/fleer family. | 0.507 |
EPM2AIP1 | ZSWIM3 | ENSP00000406027 | ENSP00000255152 | EPM2A interacting protein 1. | Zinc finger SWIM-type containing 3. | 0.463 |
HENMT1 | EPM2AIP1 | ENSP00000359049 | ENSP00000406027 | Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. | EPM2A interacting protein 1. | 0.420 |
HENMT1 | LYG1 | ENSP00000359049 | ENSP00000386923 | Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. | Lysozyme g1. | 0.479 |
HENMT1 | TTC30A | ENSP00000359049 | ENSP00000347915 | Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis. | Tetratricopeptide repeat protein 30A; Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip; Belongs to the TTC30/dfy-1/fleer family. | 0.444 |
LYG1 | DDX27 | ENSP00000386923 | ENSP00000483495 | Lysozyme g1. | Probable ATP-dependent RNA helicase DDX27; Probable ATP-dependent RNA helicase. Component of the nucleolar ribosomal RNA (rRNA) processing machinery that regulates 3' end formation of ribosomal 47S rRNA. | 0.474 |
LYG1 | EPM2AIP1 | ENSP00000386923 | ENSP00000406027 | Lysozyme g1. | EPM2A interacting protein 1. | 0.572 |