| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACSBG1 | CC2D2B | ENSP00000258873 | ENSP00000386988 | Long-chain-fatty-acid--CoA ligase ACSBG1; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids ; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily. | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.674 |
| B9D1 | CC2D2B | ENSP00000261499 | ENSP00000386988 | B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the B9D family. | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.626 |
| B9D1 | MKS1 | ENSP00000261499 | ENSP00000376827 | B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the B9D family. | Meckel syndrome type 1 protein; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. | 0.995 |
| BCOR | CC2D2B | ENSP00000367705 | ENSP00000386988 | BCL-6 corepressor; Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA- binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' ( [...] | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.457 |
| C12orf56 | C3orf22 | ENSP00000446101 | ENSP00000316644 | Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56. | Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22. | 0.570 |
| C12orf56 | CC2D2B | ENSP00000446101 | ENSP00000386988 | Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56. | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.442 |
| C3orf22 | C12orf56 | ENSP00000316644 | ENSP00000446101 | Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22. | Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56. | 0.570 |
| C3orf22 | CC2D2B | ENSP00000316644 | ENSP00000386988 | Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22. | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.491 |
| CC2D2B | ACSBG1 | ENSP00000386988 | ENSP00000258873 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Long-chain-fatty-acid--CoA ligase ACSBG1; Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids ; Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily. | 0.674 |
| CC2D2B | B9D1 | ENSP00000386988 | ENSP00000261499 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | B9 domain-containing protein 1; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the B9D family. | 0.626 |
| CC2D2B | BCOR | ENSP00000386988 | ENSP00000367705 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | BCL-6 corepressor; Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA- binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' ( [...] | 0.457 |
| CC2D2B | C12orf56 | ENSP00000386988 | ENSP00000446101 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56. | 0.442 |
| CC2D2B | C3orf22 | ENSP00000386988 | ENSP00000316644 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22. | 0.491 |
| CC2D2B | CCNJ | ENSP00000386988 | ENSP00000435373 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Cyclin-J; Cyclin J. | 0.528 |
| CC2D2B | EIF5A2 | ENSP00000386988 | ENSP00000295822 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...] | 0.666 |
| CC2D2B | MKS1 | ENSP00000386988 | ENSP00000376827 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Meckel syndrome type 1 protein; Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. | 0.533 |
| CC2D2B | POU5F1 | ENSP00000386988 | ENSP00000259915 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | 0.457 |
| CC2D2B | RALGDS | ENSP00000386988 | ENSP00000361120 | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | Ral guanine nucleotide dissociation stimulator; Stimulates the dissociation of GDP from the Ras-related RalA and RalB GTPases which allows GTP binding and activation of the GTPases. Interacts and acts as an effector molecule for R-Ras, H-Ras, K-Ras, and Rap. | 0.557 |
| CCNJ | CC2D2B | ENSP00000435373 | ENSP00000386988 | Cyclin-J; Cyclin J. | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.528 |
| EIF5A2 | CC2D2B | ENSP00000295822 | ENSP00000386988 | Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...] | Protein CC2D2B; Coiled-coil and C2 domain containing 2B. | 0.666 |
