STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C5orf52Uncharacterized protein C5orf52; Chromosome 5 open reading frame 52. (159 aa)    
Predicted Functional Partners:
CFAP97D1
Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.
      
 0.610
TMEM42
Transmembrane protein 42.
      
 0.541
CCDC24
Coiled-coil domain containing 24.
      
 0.515
TEX37
Testis-expressed sequence 37 protein; Testis expressed 37.
      
 0.507
TLCD5
TLC domain containing 5; Belongs to the TLCD5 family.
      
 0.507
CCDC116
Coiled-coil domain containing 116.
      
 0.506
KIAA0586
Protein TALPID3; Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation. Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (By similarity). Belongs to the TALPID3 family.
      
 0.506
DNAJC5G
DnaJ heat shock protein family member C5 gamma.
      
 0.476
FBXW12
F-box/WD repeat-containing protein 12; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
      
 0.448
DDX59
Probable ATP-dependent RNA helicase DDX59; DEAD-box helicase 59.
      
 0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.