| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARNTL2 | PPFIBP1 | ENSP00000266503 | ENSP00000314724 | Aryl hydrocarbon receptor nuclear translocator-like protein 2; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Liprin-beta-1; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Belongs to the liprin family. Liprin-beta subfamily. | 0.422 |
| ARNTL2 | SMCO2 | ENSP00000266503 | ENSP00000387617 | Aryl hydrocarbon receptor nuclear translocator-like protein 2; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | Single-pass membrane protein with coiled-coil domains 2. | 0.612 |
| ASAH2 | SMCO2 | ENSP00000378897 | ENSP00000387617 | Neutral ceramidase soluble form; Plasma membrane ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at neutral pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine. Together with sphingomyelinase, participates in the production of sphingosine and sphingosine-1 [...] | Single-pass membrane protein with coiled-coil domains 2. | 0.401 |
| CDRT15 | CDRT4 | ENSP00000402355 | ENSP00000482523 | CMT1A duplicated region transcript 15. | CMT1A duplicated region transcript 4. | 0.540 |
| CDRT15 | SMCO2 | ENSP00000402355 | ENSP00000387617 | CMT1A duplicated region transcript 15. | Single-pass membrane protein with coiled-coil domains 2. | 0.537 |
| CDRT4 | CDRT15 | ENSP00000482523 | ENSP00000402355 | CMT1A duplicated region transcript 4. | CMT1A duplicated region transcript 15. | 0.540 |
| CDRT4 | SMCO2 | ENSP00000482523 | ENSP00000387617 | CMT1A duplicated region transcript 4. | Single-pass membrane protein with coiled-coil domains 2. | 0.435 |
| CXorf65 | SMCO2 | ENSP00000363369 | ENSP00000387617 | Uncharacterized protein CXorf65; Chromosome X open reading frame 65. | Single-pass membrane protein with coiled-coil domains 2. | 0.440 |
| EEF1G | PPFIBP1 | ENSP00000331901 | ENSP00000314724 | Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components. | Liprin-beta-1; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Belongs to the liprin family. Liprin-beta subfamily. | 0.500 |
| EEF1G | SMCO2 | ENSP00000331901 | ENSP00000387617 | Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components. | Single-pass membrane protein with coiled-coil domains 2. | 0.566 |
| GBE1 | SMCO2 | ENSP00000410833 | ENSP00000387617 | 1,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule (Probable); Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Single-pass membrane protein with coiled-coil domains 2. | 0.439 |
| OSBPL8 | SMCO2 | ENSP00000261183 | ENSP00000387617 | Oxysterol-binding protein-related protein 8; Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. Binds oxysterol, 25- hydroxycholesterol and cholesterol. Belongs to the OSBP family. | Single-pass membrane protein with coiled-coil domains 2. | 0.470 |
| PPFIBP1 | ARNTL2 | ENSP00000314724 | ENSP00000266503 | Liprin-beta-1; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Belongs to the liprin family. Liprin-beta subfamily. | Aryl hydrocarbon receptor nuclear translocator-like protein 2; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | 0.422 |
| PPFIBP1 | EEF1G | ENSP00000314724 | ENSP00000331901 | Liprin-beta-1; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Belongs to the liprin family. Liprin-beta subfamily. | Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components. | 0.500 |
| PPFIBP1 | SMCO2 | ENSP00000314724 | ENSP00000387617 | Liprin-beta-1; May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Belongs to the liprin family. Liprin-beta subfamily. | Single-pass membrane protein with coiled-coil domains 2. | 0.651 |
| SMCO2 | ARNTL2 | ENSP00000387617 | ENSP00000266503 | Single-pass membrane protein with coiled-coil domains 2. | Aryl hydrocarbon receptor nuclear translocator-like protein 2; Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressur [...] | 0.612 |
| SMCO2 | ASAH2 | ENSP00000387617 | ENSP00000378897 | Single-pass membrane protein with coiled-coil domains 2. | Neutral ceramidase soluble form; Plasma membrane ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at neutral pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Also catalyzes the reverse reaction allowing the synthesis of ceramides from fatty acids and sphingosine. Together with sphingomyelinase, participates in the production of sphingosine and sphingosine-1 [...] | 0.401 |
| SMCO2 | CDRT15 | ENSP00000387617 | ENSP00000402355 | Single-pass membrane protein with coiled-coil domains 2. | CMT1A duplicated region transcript 15. | 0.537 |
| SMCO2 | CDRT4 | ENSP00000387617 | ENSP00000482523 | Single-pass membrane protein with coiled-coil domains 2. | CMT1A duplicated region transcript 4. | 0.435 |
| SMCO2 | CXorf65 | ENSP00000387617 | ENSP00000363369 | Single-pass membrane protein with coiled-coil domains 2. | Uncharacterized protein CXorf65; Chromosome X open reading frame 65. | 0.440 |
