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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKUB1Protein ANKUB1; Ankyrin repeat and ubiquitin domain containing 1. (502 aa)    
Predicted Functional Partners:
COMMD2
COMM domain-containing protein 2; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF- kappa-B.
      
 0.618
LRRC71
Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71.
   
  
 0.580
FAM216B
Protein FAM216B; Family with sequence similarity 216 member B; Belongs to the FAM216 family.
   
  
 0.576
ANKRD66
Ankyrin repeat domain 66.
      
 0.545
MAP3K19
Mitogen-activated protein kinase kinase kinase 19.
   
  
 0.526
C11orf88
UPF0722 protein C11orf88.
   
  
 0.521
CFC1B
Cripto, FRL-1, cryptic family 1B.
      
 0.507
TCTEX1D1
Tctex1 domain containing 1.
   
  
 0.503
STOML3
Stomatin-like protein 3; Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations; Belongs to the band 7/mec-2 family.
   
  
 0.499
DAW1
Dynein assembly factor with WDR repeat domains 1; May play a role in axonemal outer row dynein assembly. Belongs to the WD repeat WDR69 family.
   
  
 0.470
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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