node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP6V1E2 | CRIPT | ENSP00000304891 | ENSP00000238892 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. | 0.589 |
ATP6V1E2 | PIGF | ENSP00000304891 | ENSP00000281382 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Phosphatidylinositol-glycan biosynthesis class F protein; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. | 0.470 |
ATP6V1E2 | RHOQ | ENSP00000304891 | ENSP00000238738 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Rho-related GTP-binding protein RhoQ; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. | 0.491 |
ATP6V1E2 | TMEM247 | ENSP00000304891 | ENSP00000388684 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Transmembrane protein 247. | 0.731 |
ATP6V1E2 | TRIM67 | ENSP00000304891 | ENSP00000355613 | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | Tripartite motif containing 67; Belongs to the TRIM/RBCC family. | 0.431 |
C12orf73 | TMEM247 | ENSP00000367330 | ENSP00000388684 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73. | Transmembrane protein 247. | 0.473 |
C12orf73 | ZNF583 | ENSP00000367330 | ENSP00000388502 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73. | Zinc finger protein 583; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.482 |
CRIPT | ATP6V1E2 | ENSP00000238892 | ENSP00000304891 | Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | 0.589 |
CRIPT | TMEM247 | ENSP00000238892 | ENSP00000388684 | Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. | Transmembrane protein 247. | 0.689 |
CRIPT | TRIM67 | ENSP00000238892 | ENSP00000355613 | Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. | Tripartite motif containing 67; Belongs to the TRIM/RBCC family. | 0.437 |
PIGF | ATP6V1E2 | ENSP00000281382 | ENSP00000304891 | Phosphatidylinositol-glycan biosynthesis class F protein; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | 0.470 |
PIGF | TMEM247 | ENSP00000281382 | ENSP00000388684 | Phosphatidylinositol-glycan biosynthesis class F protein; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. | Transmembrane protein 247. | 0.560 |
PRR22 | TMEM247 | ENSP00000407653 | ENSP00000388684 | Proline-rich protein 22; Proline rich 22. | Transmembrane protein 247. | 0.553 |
RHOQ | ATP6V1E2 | ENSP00000238738 | ENSP00000304891 | Rho-related GTP-binding protein RhoQ; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | 0.491 |
RHOQ | TMEM247 | ENSP00000238738 | ENSP00000388684 | Rho-related GTP-binding protein RhoQ; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia. | Transmembrane protein 247. | 0.560 |
STPG4 | TMEM247 | ENSP00000408527 | ENSP00000388684 | Protein STPG4; Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote. Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC). | Transmembrane protein 247. | 0.541 |
TMEM247 | ATP6V1E2 | ENSP00000388684 | ENSP00000304891 | Transmembrane protein 247. | V-type proton ATPase subunit E 2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity). | 0.731 |
TMEM247 | C12orf73 | ENSP00000388684 | ENSP00000367330 | Transmembrane protein 247. | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73. | 0.473 |
TMEM247 | CRIPT | ENSP00000388684 | ENSP00000238892 | Transmembrane protein 247. | Cysteine-rich PDZ-binding protein; Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses. | 0.689 |
TMEM247 | PIGF | ENSP00000388684 | ENSP00000281382 | Transmembrane protein 247. | Phosphatidylinositol-glycan biosynthesis class F protein; Involved in GPI-anchor biosynthesis through the transfer of ethanolamine phosphate to the third mannose of GPI. | 0.560 |