STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBPF4Neuroblastoma breakpoint family member 4; NBPF member 4. (638 aa)    
Predicted Functional Partners:
NBPF6
Neuroblastoma breakpoint family member 6; NBPF member 6.
  
  
0.999
EVPLL
Envoplakin-like protein; Envoplakin like; Belongs to the plakin or cytolinker family.
    
 
 0.547
LRRC37A
Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A.
    
 
 0.508
PRR20B
Proline-rich protein 20A; Proline rich 20B; Belongs to the PRR20 family.
      
 0.507
PRR20A
Proline rich 20A.
      
 0.507
MAGEC1
Melanoma-associated antigen C1; MAGE family member C1.
  
 
 0.451
NOTCH2NLB
Notch homolog 2 N-terminal-like protein B; Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signal [...]
      
 0.443
FAM47A
Protein FAM47A; Family with sequence similarity 47 member A.
  
 
   0.436
CPHXL
Cytoplasmic polyadenylated homeobox like.
  
 
 
 0.428
TPTE
Putative tyrosine-protein phosphatase TPTE; Could be involved in signal transduction.
   
 
 0.424
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.