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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMIM19Small integral membrane protein 19. (107 aa)    
Predicted Functional Partners:
OR8B12
Olfactory receptor 8B12; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.571
OR8B3
Olfactory receptor 8B3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.528
ZNF484
Zinc finger protein 484; May be involved in transcriptional regulation.
      
 0.514
SMIM29
Small integral membrane protein 29.
   
  
 0.507
ANKMY2
Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia.
   
  
 0.467
TBATA
Protein TBATA; May play a role in spermatid differentiation. Modulates thymic stromal cell proliferation and thymus function.
      
 0.435
SETD9
SET domain containing 9.
   
  
 0.432
SMIM9
Small integral membrane protein 9.
      
 0.432
TBC1D8B
TBC1 domain family member 8B; Involved in vesicular recycling, probably as a RAB11B GTPase- activating protein.
      
 0.430
C10orf90
(E2-independent) E3 ubiquitin-conjugating enzyme FATS; Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Acts as a p53/TP53 activator by inhibiting MDM2 binding to p53/TP53 and stimulating non-proteolytic polyubiquitination of p53/TP53. Exhibits ubiquitin ligase (E3) activity and assemble ubiquitin polymers through 'Lys-11'- (K11-), 'Lys-29'- (K29-) and 'Lys- 63'- (K63)-linkages, independently of the ubiquitin-conjugating enzyme (E2). Promotes p53/TP53-dependent transcription of CDKN1A/p21, leading to robust checkpoint response. Mediates CDKN1A/p21 protein [...]
      
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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