Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMIM19Small integral membrane protein 19. (107 aa)    
Predicted Functional Partners:
TMTC4
Protein O-mannosyl-transferase TMTC4; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3.
   
  
 0.522
OR8B3
Olfactory receptor 8B3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.440
OR8B12
Olfactory receptor 8B12; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.429
FAM102A
Protein FAM102A; May play a role in estrogen action. Belongs to the FAM102 family.
      
 0.421
ZNF484
Zinc finger protein 484; May be involved in transcriptional regulation.
      
 0.418
ANKMY2
Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia.
   
  
 0.405
SMIM29
Small integral membrane protein 29.
   
  
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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