node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC92 | CMTR1 | ENSP00000238156 | ENSP00000362550 | Coiled-coil domain containing 92. | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. | 0.443 |
CCDC92 | NXN | ENSP00000238156 | ENSP00000337443 | Coiled-coil domain containing 92. | Nucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). Belongs to the nucleoredoxin family. | 0.408 |
CCDC92 | TTC39A | ENSP00000238156 | ENSP00000393952 | Coiled-coil domain containing 92. | Tetratricopeptide repeat domain 39A. | 0.499 |
CMTR1 | CCDC92 | ENSP00000362550 | ENSP00000238156 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. | Coiled-coil domain containing 92. | 0.443 |
CMTR1 | TTC39A | ENSP00000362550 | ENSP00000393952 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. | Tetratricopeptide repeat domain 39A. | 0.477 |
NIPAL2 | TTC39A | ENSP00000407087 | ENSP00000393952 | NIPA-like protein 2; NIPA like domain containing 2; Belongs to the NIPA family. | Tetratricopeptide repeat domain 39A. | 0.444 |
NIPAL2 | ZNF19 | ENSP00000407087 | ENSP00000288177 | NIPA-like protein 2; NIPA like domain containing 2; Belongs to the NIPA family. | Zinc finger protein 19; May be involved in transcriptional regulation. | 0.450 |
NXN | CCDC92 | ENSP00000337443 | ENSP00000238156 | Nucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). Belongs to the nucleoredoxin family. | Coiled-coil domain containing 92. | 0.408 |
NXN | TTC39A | ENSP00000337443 | ENSP00000393952 | Nucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). Belongs to the nucleoredoxin family. | Tetratricopeptide repeat domain 39A. | 0.413 |
OSBPL9 | TTC39A | ENSP00000412733 | ENSP00000393952 | Oxysterol binding protein like 9; Belongs to the OSBP family. | Tetratricopeptide repeat domain 39A. | 0.423 |
P2RY12 | TTC39A | ENSP00000307259 | ENSP00000393952 | P2Y purinoceptor 12; Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. | Tetratricopeptide repeat domain 39A. | 0.516 |
TTC39A | CCDC92 | ENSP00000393952 | ENSP00000238156 | Tetratricopeptide repeat domain 39A. | Coiled-coil domain containing 92. | 0.499 |
TTC39A | CMTR1 | ENSP00000393952 | ENSP00000362550 | Tetratricopeptide repeat domain 39A. | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. | 0.477 |
TTC39A | NIPAL2 | ENSP00000393952 | ENSP00000407087 | Tetratricopeptide repeat domain 39A. | NIPA-like protein 2; NIPA like domain containing 2; Belongs to the NIPA family. | 0.444 |
TTC39A | NXN | ENSP00000393952 | ENSP00000337443 | Tetratricopeptide repeat domain 39A. | Nucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). Belongs to the nucleoredoxin family. | 0.413 |
TTC39A | OSBPL9 | ENSP00000393952 | ENSP00000412733 | Tetratricopeptide repeat domain 39A. | Oxysterol binding protein like 9; Belongs to the OSBP family. | 0.423 |
TTC39A | P2RY12 | ENSP00000393952 | ENSP00000307259 | Tetratricopeptide repeat domain 39A. | P2Y purinoceptor 12; Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. | 0.516 |
TTC39A | UBE2Q2L | ENSP00000393952 | ENSP00000453012 | Tetratricopeptide repeat domain 39A. | Putative ubiquitin-conjugating enzyme E2Q2-like protein; Ubiquitin conjugating enzyme E2 Q2 like; Belongs to the ubiquitin-conjugating enzyme family. | 0.418 |
TTC39A | ZDHHC23 | ENSP00000393952 | ENSP00000498556 | Tetratricopeptide repeat domain 39A. | Palmitoyltransferase ZDHHC23; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting to the synaptic membrane. | 0.400 |
TTC39A | ZNF19 | ENSP00000393952 | ENSP00000288177 | Tetratricopeptide repeat domain 39A. | Zinc finger protein 19; May be involved in transcriptional regulation. | 0.546 |