STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM19A2Protein FAM19A2; Family with sequence similarity 19 member A2, C-C motif chemokine like (131 aa)    
Predicted Functional Partners:
AFAP1L2
Actin filament-associated protein 1-like 2; May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation; Pleckstrin homology domain containing
      
 0.714
XKRX
XK-related protein 2; XK related, X-linked
      
 0.619
TMEM179
Transmembrane protein 179; Belongs to the TMEM179 family
   
  
 0.599
AMER3
APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity)
   
  
 0.595
CCDC64
BICD family-like cargo adapter 1; Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity); Belongs to the BICDR family
      
 0.591
FAM171B
Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family
   
  
 0.586
OR8D4
Olfactory receptor 8D4; Odorant receptor; Olfactory receptors, family 8
      
 0.586
TMEM130
Transmembrane protein 130
   
  
 0.585
FAM189A1
Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family
   
  
 0.584
TMEM88B
Transmembrane protein 88B
   
  
 0.583
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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