STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC74BLeucine-rich repeat-containing protein 74B; Leucine rich repeat containing 74B. (392 aa)    
Predicted Functional Partners:
CDC20B
Cell division cycle 20B; Belongs to the WD repeat CDC20/Fizzy family.
   
  
 0.783
TMEM213
Transmembrane protein 213.
   
    0.742
CCT8L2
T-complex protein 1 subunit theta-like 2; Possible molecular chaperone; assists the folding of proteins upon ATP hydrolysis; Belongs to the TCP-1 chaperonin family.
      
 0.571
LMNTD1
Lamin tail domain containing 1.
   
  
 0.561
FAM47E-STBD1
FAM47E-STBD1 readthrough.
      
 0.557
GAB4
GRB2 associated binding protein family member 4; Belongs to the GAB family.
      
 0.547
RIMBP3C
RIMS-binding protein 3C; Probable component of the manchette, a microtubule-based structure which plays a key role in sperm head morphogenesis during late stages of sperm development.
      
 0.547
FAM47E
Protein FAM47E; Family with sequence similarity 47 member E.
   
  
 0.539
ATP6AP1L
V-type proton ATPase subunit S1-like protein; ATPase H+ transporting accessory protein 1 like.
   
  
 0.518
LRRC18
Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation.
      
 0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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