node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTAGE8 | PRR12 | ENSP00000417289 | ENSP00000394510 | CTAGE family member 8. | Proline-rich protein 12; Proline rich 12. | 0.510 |
FIZ1 | PRR12 | ENSP00000221665 | ENSP00000394510 | Flt3-interacting zinc finger protein 1; May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity). | Proline-rich protein 12; Proline rich 12. | 0.442 |
LMNTD2 | PRR12 | ENSP00000331167 | ENSP00000394510 | Lamin tail domain containing 2. | Proline-rich protein 12; Proline rich 12. | 0.444 |
PAGR1 | PRR12 | ENSP00000326519 | ENSP00000394510 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Proline-rich protein 12; Proline rich 12. | 0.487 |
PRR12 | CTAGE8 | ENSP00000394510 | ENSP00000417289 | Proline-rich protein 12; Proline rich 12. | CTAGE family member 8. | 0.510 |
PRR12 | FIZ1 | ENSP00000394510 | ENSP00000221665 | Proline-rich protein 12; Proline rich 12. | Flt3-interacting zinc finger protein 1; May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity). | 0.442 |
PRR12 | LMNTD2 | ENSP00000394510 | ENSP00000331167 | Proline-rich protein 12; Proline rich 12. | Lamin tail domain containing 2. | 0.444 |
PRR12 | PAGR1 | ENSP00000394510 | ENSP00000326519 | Proline-rich protein 12; Proline rich 12. | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | 0.487 |
PRR12 | PRR16 | ENSP00000394510 | ENSP00000385118 | Proline-rich protein 12; Proline rich 12. | Protein Largen; Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those encoding proteins affecting mitochondrial functions. Increases mitochondrial mass and respiration. | 0.540 |
PRR12 | PRRG2 | ENSP00000394510 | ENSP00000246794 | Proline-rich protein 12; Proline rich 12. | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain 2. | 0.704 |
PRR12 | SCAF1 | ENSP00000394510 | ENSP00000353769 | Proline-rich protein 12; Proline rich 12. | Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing. | 0.802 |
PRR12 | TP53BP1 | ENSP00000394510 | ENSP00000371475 | Proline-rich protein 12; Proline rich 12. | TP53-binding protein 1; Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)- mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1. In response to DSBs, phosphorylation by ATM promotes interaction with RIF1 and dissociation from NUDT16L1/TIRR, leading to recruitment to DSBs s [...] | 0.439 |
PRR12 | ZNF316 | ENSP00000394510 | ENSP00000477706 | Proline-rich protein 12; Proline rich 12. | Zinc finger protein 316; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.510 |
PRR12 | ZNF865 | ENSP00000394510 | ENSP00000457715 | Proline-rich protein 12; Proline rich 12. | Zinc finger protein 865; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.711 |
PRR16 | PRR12 | ENSP00000385118 | ENSP00000394510 | Protein Largen; Regulator of cell size that promotes cell size increase independently of mTOR and Hippo signaling pathways. Acts by stimulating the translation of specific mRNAs, including those encoding proteins affecting mitochondrial functions. Increases mitochondrial mass and respiration. | Proline-rich protein 12; Proline rich 12. | 0.540 |
PRRG2 | PRR12 | ENSP00000246794 | ENSP00000394510 | Transmembrane gamma-carboxyglutamic acid protein 2; Proline rich and Gla domain 2. | Proline-rich protein 12; Proline rich 12. | 0.704 |
SCAF1 | PRR12 | ENSP00000353769 | ENSP00000394510 | Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing. | Proline-rich protein 12; Proline rich 12. | 0.802 |
SCAF1 | ZNF316 | ENSP00000353769 | ENSP00000477706 | Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing. | Zinc finger protein 316; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.578 |
SCAF1 | ZNF865 | ENSP00000353769 | ENSP00000457715 | Splicing factor, arginine/serine-rich 19; May function in pre-mRNA splicing. | Zinc finger protein 865; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.656 |
TP53BP1 | PRR12 | ENSP00000371475 | ENSP00000394510 | TP53-binding protein 1; Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)- mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1. In response to DSBs, phosphorylation by ATM promotes interaction with RIF1 and dissociation from NUDT16L1/TIRR, leading to recruitment to DSBs s [...] | Proline-rich protein 12; Proline rich 12. | 0.439 |