BTBD19 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTBD19	DHX38	ENSP00000395461	ENSP00000268482	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; Probable ATP-binding RNA helicase (Probable). Involved in pre-mRNA splicing as component of the spliceosome.	0.415
BTBD19	MED26	ENSP00000395461	ENSP00000263390	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Mediator of RNA polymerase II transcription subunit 26; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.	0.409
BTBD19	MRPL19	ENSP00000395461	ENSP00000377486	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Mitochondrial ribosomal protein L19.	0.436
BTBD19	MRPL27	ENSP00000395461	ENSP00000225969	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Mitochondrial ribosomal protein L27.	0.438
BTBD19	MRPL33	ENSP00000395461	ENSP00000296102	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Mitochondrial ribosomal protein L33.	0.429
BTBD19	MRPL46	ENSP00000395461	ENSP00000312311	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family.	0.451
BTBD19	RNASEH1	ENSP00000395461	ENSP00000313350	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II ; Belongs to the RNase H family.	0.633
BTBD19	RPL13A	ENSP00000395461	ENSP00000375730	BTB/POZ domain-containing protein 19; BTB domain containing 19.	60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppre [...]	0.648
BTBD19	SNRPN	ENSP00000395461	ENSP00000494831	BTB/POZ domain-containing protein 19; BTB domain containing 19.	Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events.	0.554
BTBD19	TFPT	ENSP00000395461	ENSP00000375639	BTB/POZ domain-containing protein 19; BTB domain containing 19.	TCF3 fusion partner; Appears to promote apoptosis in a p53/TP53-independent manner.	0.434
DHX38	BTBD19	ENSP00000268482	ENSP00000395461	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; Probable ATP-binding RNA helicase (Probable). Involved in pre-mRNA splicing as component of the spliceosome.	BTB/POZ domain-containing protein 19; BTB domain containing 19.	0.415
MED26	BTBD19	ENSP00000263390	ENSP00000395461	Mediator of RNA polymerase II transcription subunit 26; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.	BTB/POZ domain-containing protein 19; BTB domain containing 19.	0.409
MRPL19	BTBD19	ENSP00000377486	ENSP00000395461	Mitochondrial ribosomal protein L19.	BTB/POZ domain-containing protein 19; BTB domain containing 19.	0.436
MRPL19	MRPL27	ENSP00000377486	ENSP00000225969	Mitochondrial ribosomal protein L19.	Mitochondrial ribosomal protein L27.	0.999
MRPL19	MRPL33	ENSP00000377486	ENSP00000296102	Mitochondrial ribosomal protein L19.	Mitochondrial ribosomal protein L33.	0.995
MRPL19	MRPL46	ENSP00000377486	ENSP00000312311	Mitochondrial ribosomal protein L19.	Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family.	0.988
MRPL19	RPL13A	ENSP00000377486	ENSP00000375730	Mitochondrial ribosomal protein L19.	60S ribosomal protein L13a; Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppre [...]	0.956
MRPL27	BTBD19	ENSP00000225969	ENSP00000395461	Mitochondrial ribosomal protein L27.	BTB/POZ domain-containing protein 19; BTB domain containing 19.	0.438
MRPL27	MRPL19	ENSP00000225969	ENSP00000377486	Mitochondrial ribosomal protein L27.	Mitochondrial ribosomal protein L19.	0.999
MRPL27	MRPL33	ENSP00000225969	ENSP00000296102	Mitochondrial ribosomal protein L27.	Mitochondrial ribosomal protein L33.	0.999