STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRR23CProline-rich protein 23C; Proline rich 23C; Belongs to the PRR23 family. (262 aa)    
Predicted Functional Partners:
RSPRY1
Ring finger and SPRY domain containing 1.
      
 0.567
C8orf86
Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.
   
    0.531
FAM90A10P
Putative protein FAM90A10P; Belongs to the FAM90 family.
      
 0.529
SPAG11B
Sperm associated antigen 11B.
      
 0.523
DEFB106A
Defensin beta 106A.
      
 0.505
DEFB107A
Beta-defensin 107; Has antibacterial activity.
      
 0.502
CEP95
Centrosomal protein 95.
      
 0.479
DEFB105A
Beta-defensin 105; Has antibacterial activity.
      
 0.461
DEFB106B
Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family.
      
 0.441
USP17L4
Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4; Ubiquitin specific peptidase 17 like family member 4.
      
 0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.