node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKMY2 | BZW2 | ENSP00000303570 | ENSP00000397249 | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia. | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | 0.598 |
ANKMY2 | LRRC72 | ENSP00000303570 | ENSP00000384971 | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia. | Leucine-rich repeat-containing protein 72; Leucine rich repeat containing 72. | 0.629 |
ANKMY2 | SNX13 | ENSP00000303570 | ENSP00000398789 | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia. | Sorting nexin-13; May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas. | 0.563 |
ANKMY2 | TSPAN13 | ENSP00000303570 | ENSP00000262067 | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia. | Tetraspanin-13; Tetraspanin 13. | 0.647 |
BZW1 | BZW2 | ENSP00000394316 | ENSP00000397249 | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly. | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | 0.839 |
BZW1 | EIF2S2 | ENSP00000394316 | ENSP00000364119 | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly. | Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | 0.439 |
BZW1 | EIF5 | ENSP00000394316 | ENSP00000216554 | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly. | Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). | 0.645 |
BZW1 | IPO11 | ENSP00000394316 | ENSP00000386992 | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly. | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] | 0.528 |
BZW2 | ANKMY2 | ENSP00000397249 | ENSP00000303570 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Ankyrin repeat and MYND domain-containing protein 2; May be involved in the trafficking of signaling proteins to the cilia. | 0.598 |
BZW2 | BZW1 | ENSP00000397249 | ENSP00000394316 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly. | 0.839 |
BZW2 | EIF2B1 | ENSP00000397249 | ENSP00000416250 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | 0.502 |
BZW2 | EIF2S2 | ENSP00000397249 | ENSP00000364119 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | 0.633 |
BZW2 | EIF5 | ENSP00000397249 | ENSP00000216554 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). | 0.610 |
BZW2 | IPO11 | ENSP00000397249 | ENSP00000386992 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Importin-11; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis re [...] | 0.539 |
BZW2 | LRRC72 | ENSP00000397249 | ENSP00000384971 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Leucine-rich repeat-containing protein 72; Leucine rich repeat containing 72. | 0.419 |
BZW2 | MARK3 | ENSP00000397249 | ENSP00000411397 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | MAP/microtubule affinity-regulating kinase 3; Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the [...] | 0.419 |
BZW2 | SNX13 | ENSP00000397249 | ENSP00000398789 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Sorting nexin-13; May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas. | 0.570 |
BZW2 | TSPAN13 | ENSP00000397249 | ENSP00000262067 | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | Tetraspanin-13; Tetraspanin 13. | 0.615 |
EIF2B1 | BZW2 | ENSP00000416250 | ENSP00000397249 | Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. | 0.502 |
EIF2B1 | EIF2S2 | ENSP00000416250 | ENSP00000364119 | Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | Eukaryotic translation initiation factor 2 subunit 2; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | 0.999 |