| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP11A | ATP9B | ENSP00000420387 | ENSP00000398076 | Probable phospholipid-transporting ATPase IH; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | 0.484 |
| ATP11A | TMEM30A | ENSP00000420387 | ENSP00000230461 | Probable phospholipid-transporting ATPase IH; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. | Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...] | 0.999 |
| ATP11A | TMEM30B | ENSP00000420387 | ENSP00000450842 | Probable phospholipid-transporting ATPase IH; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. | Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...] | 0.947 |
| ATP7B | ATP9B | ENSP00000242839 | ENSP00000398076 | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | 0.493 |
| ATP9B | ATP11A | ENSP00000398076 | ENSP00000420387 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Probable phospholipid-transporting ATPase IH; Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). May be involved in the uptake of farnesyltransferase inhibitor drugs, such as lonafarnib. | 0.484 |
| ATP9B | ATP7B | ENSP00000398076 | ENSP00000242839 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Copper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. | 0.493 |
| ATP9B | B4GAT1 | ENSP00000398076 | ENSP00000309096 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose- beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for [...] | 0.518 |
| ATP9B | DOP1A | ENSP00000398076 | ENSP00000237163 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family. | 0.558 |
| ATP9B | KIAA1328 | ENSP00000398076 | ENSP00000280020 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes. | 0.513 |
| ATP9B | MON2 | ENSP00000398076 | ENSP00000377250 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes. | 0.690 |
| ATP9B | SLC66A2 | ENSP00000398076 | ENSP00000380880 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Solute carrier family 66 member 2. | 0.746 |
| ATP9B | TMEM184A | ENSP00000398076 | ENSP00000297477 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity). | 0.505 |
| ATP9B | TMEM30A | ENSP00000398076 | ENSP00000230461 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...] | 0.671 |
| ATP9B | TMEM30B | ENSP00000398076 | ENSP00000450842 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...] | 0.641 |
| B4GAT1 | ATP9B | ENSP00000309096 | ENSP00000398076 | Beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose- beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for [...] | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | 0.518 |
| B4GAT1 | TMEM184A | ENSP00000309096 | ENSP00000297477 | Beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose- beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for [...] | Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity). | 0.435 |
| DOP1A | ATP9B | ENSP00000237163 | ENSP00000398076 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family. | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | 0.558 |
| DOP1A | MON2 | ENSP00000237163 | ENSP00000377250 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family. | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes. | 0.965 |
| DOP1A | SLC66A2 | ENSP00000237163 | ENSP00000380880 | Protein dopey-1; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family. | Solute carrier family 66 member 2. | 0.686 |
| KIAA1328 | ATP9B | ENSP00000280020 | ENSP00000398076 | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes. | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B. | 0.513 |
