ZBED5 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC123	ZBED5	ENSP00000281141	ENSP00000398106	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	Zinc finger BED-type containing 5.	0.471
CDC123	ZMYM1	ENSP00000281141	ENSP00000496876	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	Zinc finger MYM-type containing 1.	0.464
HSFX4	LINC01862	ENSP00000489814	ENSP00000499970	Heat shock transcription factor family, X-linked member 4.	Long intergenic non-protein coding RNA 1862.	0.726
HSFX4	ZBED5	ENSP00000489814	ENSP00000398106	Heat shock transcription factor family, X-linked member 4.	Zinc finger BED-type containing 5.	0.465
LINC01862	HSFX4	ENSP00000499970	ENSP00000489814	Long intergenic non-protein coding RNA 1862.	Heat shock transcription factor family, X-linked member 4.	0.726
LINC01862	ZBED5	ENSP00000499970	ENSP00000398106	Long intergenic non-protein coding RNA 1862.	Zinc finger BED-type containing 5.	0.570
MECP2	ZBED4	ENSP00000395535	ENSP00000216268	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	Zinc finger BED-type containing 4.	0.476
MECP2	ZBED5	ENSP00000395535	ENSP00000398106	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	Zinc finger BED-type containing 5.	0.476
XPO7	ZBED5	ENSP00000252512	ENSP00000398106	Exportin-7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate ano [...]	Zinc finger BED-type containing 5.	0.460
XPO7	ZMYM1	ENSP00000252512	ENSP00000496876	Exportin-7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate ano [...]	Zinc finger MYM-type containing 1.	0.472
ZBED4	MECP2	ENSP00000216268	ENSP00000395535	Zinc finger BED-type containing 4.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	0.476
ZBED4	ZBED5	ENSP00000216268	ENSP00000398106	Zinc finger BED-type containing 4.	Zinc finger BED-type containing 5.	0.440
ZBED4	ZBED6CL	ENSP00000216268	ENSP00000343242	Zinc finger BED-type containing 4.	ZBED6 C-terminal-like protein; ZBED6 C-terminal like.	0.548
ZBED5	CDC123	ENSP00000398106	ENSP00000281141	Zinc finger BED-type containing 5.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	0.471
ZBED5	HSFX4	ENSP00000398106	ENSP00000489814	Zinc finger BED-type containing 5.	Heat shock transcription factor family, X-linked member 4.	0.465
ZBED5	LINC01862	ENSP00000398106	ENSP00000499970	Zinc finger BED-type containing 5.	Long intergenic non-protein coding RNA 1862.	0.570
ZBED5	MECP2	ENSP00000398106	ENSP00000395535	Zinc finger BED-type containing 5.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)- containing DNA, with a preference for 5-methylcytosine (5mC).	0.476
ZBED5	XPO7	ENSP00000398106	ENSP00000252512	Zinc finger BED-type containing 5.	Exportin-7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate ano [...]	0.460
ZBED5	ZBED4	ENSP00000398106	ENSP00000216268	Zinc finger BED-type containing 5.	Zinc finger BED-type containing 4.	0.440
ZBED5	ZBED6	ENSP00000398106	ENSP00000447879	Zinc finger BED-type containing 5.	Zinc finger BED domain-containing protein 6; Transcriptional repressor which binds to the consensus sequence 5'-GCTCGC-3' and represses transcription of IGF2. May also regulate expression of other target genes containing this consensus binding site (By similarity).	0.402