node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C16orf90 | C3orf52 | ENSP00000401335 | ENSP00000399392 | Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90. | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.474 |
C3orf52 | C16orf90 | ENSP00000399392 | ENSP00000401335 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90. | 0.474 |
C3orf52 | C4orf19 | ENSP00000399392 | ENSP00000371408 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19. | 0.429 |
C3orf52 | CLVS2 | ENSP00000399392 | ENSP00000275162 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | 0.415 |
C3orf52 | LIPH | ENSP00000399392 | ENSP00000296252 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | Lipase member H; Hydrolyzes specifically phosphatidic acid (PA) to produce 2- acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). Belongs to the AB hydrolase superfamily. Lipase family. | 0.649 |
C3orf52 | SLITRK1 | ENSP00000399392 | ENSP00000366288 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. | 0.446 |
C3orf52 | TMPRSS2 | ENSP00000399392 | ENSP00000381588 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | Transmembrane protease serine 2 non-catalytic chain; Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike gl [...] | 0.606 |
C3orf52 | ZNF343 | ENSP00000399392 | ENSP00000482819 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.402 |
C4orf19 | C3orf52 | ENSP00000371408 | ENSP00000399392 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19. | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.429 |
CLVS2 | C3orf52 | ENSP00000275162 | ENSP00000399392 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.415 |
CLVS2 | ZNF343 | ENSP00000275162 | ENSP00000482819 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.408 |
LIPH | C3orf52 | ENSP00000296252 | ENSP00000399392 | Lipase member H; Hydrolyzes specifically phosphatidic acid (PA) to produce 2- acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG). Belongs to the AB hydrolase superfamily. Lipase family. | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.649 |
SLITRK1 | C3orf52 | ENSP00000366288 | ENSP00000399392 | SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.446 |
TMPRSS2 | C3orf52 | ENSP00000381588 | ENSP00000399392 | Transmembrane protease serine 2 non-catalytic chain; Serine protease that proteolytically cleaves and activates the viral spike glycoproteins which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence. Facilitates human SARS coronavirus (SARS-CoV) infection via two independent mechanisms, proteolytic cleavage of ACE2, which might promote viral uptake, and cleavage of coronavirus spike gl [...] | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.606 |
ZNF343 | C3orf52 | ENSP00000482819 | ENSP00000399392 | Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52. | 0.402 |
ZNF343 | CLVS2 | ENSP00000482819 | ENSP00000275162 | Zinc finger protein 343; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). | 0.408 |