STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBEAL1Neurobeachin-like protein 1; Neurobeachin like 1; Belongs to the WD repeat neurobeachin family. (2694 aa)    
Predicted Functional Partners:
ICA1L
Islet cell autoantigen 1 like.
   
  
 0.693
FAM117B
Protein FAM117B; Family with sequence similarity 117 member B.
   
  
 0.654
WDR12
Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
  
 0.521
CARF
Calcium-responsive transcription factor; Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
   
  
 0.474
ZBTB44
Zinc finger and BTB domain-containing protein 44; May be involved in transcriptional regulation.
      
 0.472
PMF1-BGLAP
PMF1-BGLAP readthrough.
      
 0.448
C1QL1
C1q-related factor; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).
      
 0.447
SERTAD4
SERTA domain containing 4.
   
  
 0.447
TRIM65
Tripartite motif containing 65; Belongs to the TRIM/RBCC family.
      
 0.437
SACS
Sacsin; Co-chaperone which acts as a regulator of the Hsp70 chaperone machinery and may be involved in the processing of other ataxia-linked proteins.
   
  
 0.431
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.