node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LRRC75B | SLC2A11-2 | ENSP00000320520 | ENSP00000400325 | Leucine-rich repeat-containing protein 75B; Leucine rich repeat containing 75B. | MFS domain-containing protein. | 0.418 |
SLC2A10 | SLC2A11-2 | ENSP00000352216 | ENSP00000400325 | Solute carrier family 2, facilitated glucose transporter member 10; Facilitative glucose transporter required for the development of the cardiovascular system; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | MFS domain-containing protein. | 0.683 |
SLC2A10 | SLC2A8 | ENSP00000352216 | ENSP00000362469 | Solute carrier family 2, facilitated glucose transporter member 10; Facilitative glucose transporter required for the development of the cardiovascular system; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Solute carrier family 2, facilitated glucose transporter member 8; Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the transport of dehydroascorbate. | 0.433 |
SLC2A11-2 | LRRC75B | ENSP00000400325 | ENSP00000320520 | MFS domain-containing protein. | Leucine-rich repeat-containing protein 75B; Leucine rich repeat containing 75B. | 0.418 |
SLC2A11-2 | SLC2A10 | ENSP00000400325 | ENSP00000352216 | MFS domain-containing protein. | Solute carrier family 2, facilitated glucose transporter member 10; Facilitative glucose transporter required for the development of the cardiovascular system; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | 0.683 |
SLC2A11-2 | SLC2A12 | ENSP00000400325 | ENSP00000275230 | MFS domain-containing protein. | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | 0.873 |
SLC2A11-2 | SLC2A13 | ENSP00000400325 | ENSP00000280871 | MFS domain-containing protein. | Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.792 |
SLC2A11-2 | SLC2A6 | ENSP00000400325 | ENSP00000360966 | MFS domain-containing protein. | Solute carrier family 2, facilitated glucose transporter member 6; Probable sugar transporter that acts as a regulator of glycolysis in macrophages (Probable). Does not transport glucose. | 0.849 |
SLC2A11-2 | SLC2A8 | ENSP00000400325 | ENSP00000362469 | MFS domain-containing protein. | Solute carrier family 2, facilitated glucose transporter member 8; Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the transport of dehydroascorbate. | 0.864 |
SLC2A11-2 | SLC5A1 | ENSP00000400325 | ENSP00000266088 | MFS domain-containing protein. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. | 0.491 |
SLC2A11-2 | SLC5A11 | ENSP00000400325 | ENSP00000289932 | MFS domain-containing protein. | Sodium/myo-inositol cotransporter 2; Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D- chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney; Belongs to the sodium:solute symporter (SSF) (TC 2 [...] | 0.446 |
SLC2A11-2 | SLC5A4 | ENSP00000400325 | ENSP00000266086 | MFS domain-containing protein. | Solute carrier family 5 member 4; Has electrogenic activity in response to glucose, and may function as a glucose sensor. Mediates influx of sodium ions into the cell but does not transport sugars. Also potently activated by imino sugars such as deoxynojirimycin (DNJ). Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.542 |
SLC2A11-2 | SLC5A9 | ENSP00000400325 | ENSP00000236495 | MFS domain-containing protein. | Sodium/glucose cotransporter 4; Involved in sodium-dependent transport of D-mannose, D- glucose and D-fructose; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.534 |
SLC2A12 | SLC2A11-2 | ENSP00000275230 | ENSP00000400325 | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | MFS domain-containing protein. | 0.873 |
SLC2A12 | SLC2A6 | ENSP00000275230 | ENSP00000360966 | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Solute carrier family 2, facilitated glucose transporter member 6; Probable sugar transporter that acts as a regulator of glycolysis in macrophages (Probable). Does not transport glucose. | 0.417 |
SLC2A12 | SLC5A1 | ENSP00000275230 | ENSP00000266088 | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Sodium/glucose cotransporter 1; Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. | 0.625 |
SLC2A12 | SLC5A11 | ENSP00000275230 | ENSP00000289932 | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Sodium/myo-inositol cotransporter 2; Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D- chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney; Belongs to the sodium:solute symporter (SSF) (TC 2 [...] | 0.482 |
SLC2A12 | SLC5A4 | ENSP00000275230 | ENSP00000266086 | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Solute carrier family 5 member 4; Has electrogenic activity in response to glucose, and may function as a glucose sensor. Mediates influx of sodium ions into the cell but does not transport sugars. Also potently activated by imino sugars such as deoxynojirimycin (DNJ). Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.497 |
SLC2A12 | SLC5A9 | ENSP00000275230 | ENSP00000236495 | Solute carrier family 2, facilitated glucose transporter member 12; Insulin-independent facilitative glucose transporter. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Sodium/glucose cotransporter 4; Involved in sodium-dependent transport of D-mannose, D- glucose and D-fructose; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.438 |
SLC2A13 | SLC2A11-2 | ENSP00000280871 | ENSP00000400325 | Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | MFS domain-containing protein. | 0.792 |