C1orf159 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf159	CDC123	ENSP00000368644	ENSP00000281141	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	0.457
C1orf159	COG1	ENSP00000368644	ENSP00000299886	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	0.483
C1orf159	DNHD1	ENSP00000368644	ENSP00000254579	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Dynein heavy chain domain 1.	0.430
C1orf159	FAM149B1	ENSP00000368644	ENSP00000242505	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Protein FAM149B1; Family with sequence similarity 149 member B1.	0.420
C1orf159	HNRNPH1	ENSP00000368644	ENSP00000349168	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).	0.457
C1orf159	HNRNPL	ENSP00000368644	ENSP00000221419	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Heterogeneous nuclear ribonucleoprotein L; Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.	0.467
C1orf159	LGALS8	ENSP00000368644	ENSP00000435460	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Galectin-8; Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruse [...]	0.690
C1orf159	LRP8	ENSP00000368644	ENSP00000303634	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Low-density lipoprotein receptor-related protein 8; Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brai [...]	0.424
C1orf159	RNF223	ENSP00000368644	ENSP00000410533	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Ring finger protein 223.	0.418
C1orf159	TOMM6	ENSP00000368644	ENSP00000381859	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	Mitochondrial import receptor subunit TOM6 homolog; Translocase of outer mitochondrial membrane 6.	0.437
CDC123	C1orf159	ENSP00000281141	ENSP00000368644	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.457
CDC123	HNRNPH1	ENSP00000281141	ENSP00000349168	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).	0.475
CDC123	HNRNPL	ENSP00000281141	ENSP00000221419	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	Heterogeneous nuclear ribonucleoprotein L; Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.	0.472
COG1	C1orf159	ENSP00000299886	ENSP00000368644	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.483
DNHD1	C1orf159	ENSP00000254579	ENSP00000368644	Dynein heavy chain domain 1.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.430
FAM149B1	C1orf159	ENSP00000242505	ENSP00000368644	Protein FAM149B1; Family with sequence similarity 149 member B1.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.420
HNRNPH1	C1orf159	ENSP00000349168	ENSP00000368644	Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.457
HNRNPH1	CDC123	ENSP00000349168	ENSP00000281141	Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).	Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle.	0.475
HNRNPH1	HNRNPL	ENSP00000349168	ENSP00000221419	Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).	Heterogeneous nuclear ribonucleoprotein L; Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.	0.996
HNRNPL	C1orf159	ENSP00000221419	ENSP00000368644	Heterogeneous nuclear ribonucleoprotein L; Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter.	Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159.	0.467