STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC69Leucine-rich repeat-containing protein 69; Leucine rich repeat containing 69. (191 aa)    
Predicted Functional Partners:
GDPGP1
GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
   
    0.665
PRRG3
Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain 3.
   
    0.650
SHOX
Short stature homeobox protein; Controls fundamental aspects of growth and development; Belongs to the paired homeobox family. Bicoid subfamily.
   
    0.624
ATAD3C
ATPase family AAA domain containing 3C; Belongs to the AAA ATPase family.
   
    0.540
FAM241B
Protein FAM241B; May play a role in lysosome homeostasis. Belongs to the FAM241 family.
      
 0.527
FAM149B1
Protein FAM149B1; Family with sequence similarity 149 member B1.
      
 0.479
LCMT2
tRNA wybutosine-synthesizing protein 4; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
   
    0.467
LRRC46
Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46.
   
  
 0.453
KCNJ3
G protein-activated inward rectifier potassium channel 1; This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating t [...]
   
    0.443
PLPPR2
Phospholipid phosphatase-related protein type 2; Phospholipid phosphatase related 2.
      
 0.432
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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