C16orf90 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C16orf90	C19orf67	ENSP00000401335	ENSP00000449137	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family.	0.443
C16orf90	C1orf210	ENSP00000401335	ENSP00000430918	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	Type III endosome membrane protein TEMP; May be involved in membrane trafficking between endosomes and plasma membrane.	0.430
C16orf90	C1orf52	ENSP00000401335	ENSP00000419417	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	UPF0690 protein C1orf52; Chromosome 1 open reading frame 52; Belongs to the UPF0690 family.	0.430
C16orf90	C20orf141	ENSP00000401335	ENSP00000369963	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	0.519
C16orf90	C20orf173	ENSP00000401335	ENSP00000403566	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	Uncharacterized protein C20orf173; Chromosome 20 open reading frame 173.	0.445
C16orf90	C4orf45	ENSP00000401335	ENSP00000412215	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	Uncharacterized protein C4orf45; Chromosome 4 open reading frame 45.	0.439
C16orf90	IQCF3	ENSP00000401335	ENSP00000409373	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	IQ motif containing F3.	0.435
C16orf90	RNF123	ENSP00000401335	ENSP00000328287	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	E3 ubiquitin-protein ligase RNF123; Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Promotes the ubiquitination and proteasome- mediated degradation of CDKN1B which is the cyclin-dependent kinase inhibitor at the G0-G1 transition of the cell cycle. Functions also as an inhibitor of innate antiviral signaling mediated by DDX58 and IFIH1 independently of its E3 ligase activity. Interacts with the N-terminal CARD domains of DDX58 and IFIH1 and competes with the downstream adapter MAVS.	0.546
C16orf90	SPANXN5	ENSP00000401335	ENSP00000364661	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	Sperm protein associated with the nucleus on the X chromosome N5; SPANX family member N5; Belongs to the SPAN-X family.	0.426
C16orf90	WFDC11	ENSP00000401335	ENSP00000348968	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	Protein WFDC11; WAP four-disulfide core domain 11.	0.553
C19orf67	C16orf90	ENSP00000449137	ENSP00000401335	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family.	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	0.443
C19orf67	C20orf141	ENSP00000449137	ENSP00000369963	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family.	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	0.515
C19orf67	C20orf173	ENSP00000449137	ENSP00000403566	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family.	Uncharacterized protein C20orf173; Chromosome 20 open reading frame 173.	0.441
C19orf67	C4orf45	ENSP00000449137	ENSP00000412215	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family.	Uncharacterized protein C4orf45; Chromosome 4 open reading frame 45.	0.466
C1orf210	C16orf90	ENSP00000430918	ENSP00000401335	Type III endosome membrane protein TEMP; May be involved in membrane trafficking between endosomes and plasma membrane.	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	0.430
C1orf210	C1orf52	ENSP00000430918	ENSP00000419417	Type III endosome membrane protein TEMP; May be involved in membrane trafficking between endosomes and plasma membrane.	UPF0690 protein C1orf52; Chromosome 1 open reading frame 52; Belongs to the UPF0690 family.	0.436
C1orf52	C16orf90	ENSP00000419417	ENSP00000401335	UPF0690 protein C1orf52; Chromosome 1 open reading frame 52; Belongs to the UPF0690 family.	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	0.430
C1orf52	C1orf210	ENSP00000419417	ENSP00000430918	UPF0690 protein C1orf52; Chromosome 1 open reading frame 52; Belongs to the UPF0690 family.	Type III endosome membrane protein TEMP; May be involved in membrane trafficking between endosomes and plasma membrane.	0.436
C20orf141	C16orf90	ENSP00000369963	ENSP00000401335	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90.	0.519
C20orf141	C19orf67	ENSP00000369963	ENSP00000449137	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family.	0.515