C11orf94 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf55	C11orf94	ENSP00000409225	ENSP00000401498	Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	0.646
C10orf55	GYPE	ENSP00000409225	ENSP00000351430	Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.	Glycophorin-E; This protein is a minor sialoglycoprotein in human erythrocyte membranes; Belongs to the glycophorin-A family.	0.549
C10orf55	SFTA2	ENSP00000409225	ENSP00000351989	Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.	Surfactant-associated protein 2; Putative surfactant protein.	0.559
C10orf55	SLN	ENSP00000409225	ENSP00000435380	Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.	Sarcolipin; Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle- based, non-shivering thermogenesis (By similarity). Belongs to the sarcolipin family.	0.497
C10orf55	TAC4	ENSP00000409225	ENSP00000334042	Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.	Endokinin-A/B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.	0.547
C11orf94	C10orf55	ENSP00000401498	ENSP00000409225	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Uncharacterized protein C10orf55; Chromosome 10 open reading frame 55.	0.646
C11orf94	C20orf141	ENSP00000401498	ENSP00000369963	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	0.645
C11orf94	DEFB113	ENSP00000401498	ENSP00000381703	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.	0.583
C11orf94	GYPE	ENSP00000401498	ENSP00000351430	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Glycophorin-E; This protein is a minor sialoglycoprotein in human erythrocyte membranes; Belongs to the glycophorin-A family.	0.636
C11orf94	MRAP	ENSP00000401498	ENSP00000382684	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Melanocortin-2 receptor accessory protein; Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.	0.583
C11orf94	OR1J4	ENSP00000401498	ENSP00000343521	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Olfactory receptor 1J4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.577
C11orf94	SFTA2	ENSP00000401498	ENSP00000351989	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Surfactant-associated protein 2; Putative surfactant protein.	0.586
C11orf94	SLN	ENSP00000401498	ENSP00000435380	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Sarcolipin; Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle- based, non-shivering thermogenesis (By similarity). Belongs to the sarcolipin family.	0.632
C11orf94	TAC4	ENSP00000401498	ENSP00000334042	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Endokinin-A/B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.	0.584
C11orf94	TMEM86B	ENSP00000401498	ENSP00000321038	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Lysoplasmalogenase; Enzyme catalyzing the degradation of lysoplasmalogen. Lysoplasmalogens are formed by the hydrolysis of the abundant membrane glycerophospholipids plasmalogens. May control the respective levels of plasmalogens and lysoplasmalogens in cells and modulate cell membrane properties; Belongs to the TMEM86 family.	0.580
C20orf141	C11orf94	ENSP00000369963	ENSP00000401498	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	0.645
C20orf141	GYPE	ENSP00000369963	ENSP00000351430	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	Glycophorin-E; This protein is a minor sialoglycoprotein in human erythrocyte membranes; Belongs to the glycophorin-A family.	0.635
C20orf141	MRAP	ENSP00000369963	ENSP00000382684	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	Melanocortin-2 receptor accessory protein; Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.	0.499
C20orf141	OR1J4	ENSP00000369963	ENSP00000343521	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	Olfactory receptor 1J4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.499
C20orf141	TAC4	ENSP00000369963	ENSP00000334042	Uncharacterized protein C20orf141; Chromosome 20 open reading frame 141.	Endokinin-A/B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.	0.567