STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACSF2Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation. (640 aa)    
Predicted Functional Partners:
MRPL21
Mitochondrial ribosomal protein L21.
   
   0.939
MRPL3
Mitochondrial ribosomal protein L3.
   
 
 0.938
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.
   
 
 0.937
MRPL47
Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.934
MRPL17
Mitochondrial ribosomal protein L17.
   
   0.933
MRPL11
Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.
   
   0.933
MRPL46
Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family.
   
   0.933
MRPL43
Mitochondrial ribosomal protein L43.
   
   0.933
MRPL24
Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.
   
   0.933
DAP3
28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death; Belongs to the mitochondrion-specific ribosomal protein mS29 family.
   
   0.847
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (12%) [HD]