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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM235Transmembrane protein 235; Belongs to the PMP-22/EMP/MP20 family. (223 aa)    
Predicted Functional Partners:
OPALIN
Opalin; Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
   
  
 0.859
MAG
Myelin-associated glycoprotein; Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid- containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on [...]
   
  
 0.799
OR4E2
Olfactory receptor 4E2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.590
OR10Z1
Olfactory receptor 10Z1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.582
FAM166B
Protein FAM166B; Family with sequence similarity 166 member B; Belongs to the UPF0605 family.
      
 0.577
TMEM151B
Transmembrane protein 151B; Belongs to the TMEM151 family.
   
  
 0.572
TMEM151A
Transmembrane protein 151A.
   
  
 0.565
SLC4A10
Sodium-driven chloride bicarbonate exchanger; Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH. Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride (By similarity). Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange. Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid (By similarity). Reduces the excitability o [...]
   
  
 0.555
OR6K6
Olfactory receptor 6K6; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.543
OR5C1
Olfactory receptor 5C1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.542
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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